Detailed information NTG0578507

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KRH49_RS07895
• Genome accession: NZ_CP076843
• Coordinates: 1612783..1613826 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 55-100-003
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1607783..1618826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRH49_RS07865 (KRH49_07865)	-	1608204..1609460 (-)	1257	WP_074347694.1	aminopeptidase	-
KRH49_RS07870 (KRH49_07870)	-	1609463..1609663 (-)	201	WP_000180460.1	DUF1128 family protein	-
KRH49_RS07875 (KRH49_07875)	-	1609810..1610274 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KRH49_RS07880 (KRH49_07880)	-	1610281..1610556 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KRH49_RS07885 (KRH49_07885)	-	1610834..1612051 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
KRH49_RS07890 (KRH49_07890)	vraR	1612164..1612793 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KRH49_RS07895 (KRH49_07895)	vraS	1612783..1613826 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KRH49_RS07900 (KRH49_07900)	liaF	1613823..1614524 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KRH49_RS07905 (KRH49_07905)	-	1614539..1614925 (-)	387	WP_001110182.1	hypothetical protein	-
KRH49_RS07910 (KRH49_07910)	map	1615142..1615900 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
KRH49_RS07915 (KRH49_07915)	-	1616484..1617470 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
KRH49_RS07920 (KRH49_07920)	-	1617659..1618072 (-)	414	WP_025174370.1	hypothetical protein	-
KRH49_RS07925 (KRH49_07925)	-	1618101..1618211 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=578507 KRH49_RS07895 WP_001017131.1 1612783..1613826(-) (vraS) [Staphylococcus aureus strain 55-100-003]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=578507 KRH49_RS07895 WP_001017131.1 1612783..1613826(-) (vraS) [Staphylococcus aureus strain 55-100-003]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1