Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KRH48_RS10925 Genome accession   NZ_CP076839
Coordinates   2296614..2297330 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 55-100-016     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2291614..2302330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRH48_RS10910 (KRH48_10910) - 2292700..2293650 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  KRH48_RS10915 (KRH48_10915) - 2293800..2295284 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  KRH48_RS10920 (KRH48_10920) - 2295281..2296240 (+) 960 WP_001253294.1 carbohydrate kinase -
  KRH48_RS10925 (KRH48_10925) agrA 2296614..2297330 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KRH48_RS10930 (KRH48_10930) agrC 2297349..2298641 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  KRH48_RS10935 (KRH48_10935) agrD 2298666..2298806 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KRH48_RS10940 (KRH48_10940) agrB 2298803..2299372 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  KRH48_RS13975 hld 2299662..2299742 (+) 81 WP_000046022.1 delta-hemolysin -
  KRH48_RS10950 (KRH48_10950) - 2300344..2301129 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  KRH48_RS10955 (KRH48_10955) - 2301437..2302063 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=578454 KRH48_RS10925 WP_000688492.1 2296614..2297330(-) (agrA) [Staphylococcus aureus strain 55-100-016]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=578454 KRH48_RS10925 WP_000688492.1 2296614..2297330(-) (agrA) [Staphylococcus aureus strain 55-100-016]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1