Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   KQ224_RS09180 Genome accession   NZ_CP076721
Coordinates   1780493..1782739 (-) Length   748 a.a.
NCBI ID   WP_216806472.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1775493..1787739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS09160 (KQ224_09160) - 1776218..1776661 (+) 444 WP_171989210.1 GNAT family N-acetyltransferase -
  KQ224_RS09165 (KQ224_09165) ileS 1776672..1779461 (+) 2790 WP_216806470.1 isoleucine--tRNA ligase -
  KQ224_RS09170 (KQ224_09170) - 1779524..1779832 (-) 309 WP_171989209.1 DUF1827 family protein -
  KQ224_RS09175 (KQ224_09175) - 1779879..1780346 (-) 468 WP_216806471.1 NUDIX hydrolase -
  KQ224_RS09180 (KQ224_09180) clpE 1780493..1782739 (-) 2247 WP_216806472.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  KQ224_RS09185 (KQ224_09185) - 1783068..1783298 (+) 231 WP_024392448.1 DUF1797 family protein -
  KQ224_RS09190 (KQ224_09190) - 1783417..1784091 (+) 675 WP_216806473.1 amino acid ABC transporter permease -
  KQ224_RS09195 (KQ224_09195) - 1784099..1784833 (+) 735 WP_174845581.1 amino acid ABC transporter ATP-binding protein -
  KQ224_RS09200 (KQ224_09200) - 1784962..1785813 (+) 852 WP_130554559.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  KQ224_RS09205 (KQ224_09205) - 1785894..1786802 (-) 909 WP_171989204.1 neutral zinc metallopeptidase -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 83388.88 Da        Isoelectric Point: 5.2853

>NTDB_id=577605 KQ224_RS09180 WP_216806472.1 1780493..1782739(-) (clpE) [Streptococcus parasuis strain H35]
MLCTNCKINDATIHLYTNMNGKQQKVDLCHNCYQIMKTDPNNAILRGLGENLTNPNNMDPFSEFFNHLGGYPGNTPAGKN
RDQTPPTQAGGGNGGGRFNQPNVGQTQTVPQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQNKYQDYHHVKYS
PEAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKEQATRDEDYEKAAYYRDQIAKY
KEMQKATISEEDIPLITEKEIEAIIEQKTNIPVGELKEKEQSQLIHLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLGNFFTPEFM
NRFDGIIEFQPLTKENLLQIVSLMLEDVNRRLSTNGIRLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYL
ENPNEKDLRAVMTNKGTIQIKAQPPKEK

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=577605 KQ224_RS09180 WP_216806472.1 1780493..1782739(-) (clpE) [Streptococcus parasuis strain H35]
ATGCTCTGTACAAACTGTAAAATAAATGATGCCACCATTCATCTCTATACAAATATGAATGGAAAACAACAGAAAGTTGA
CCTTTGCCATAATTGTTATCAAATTATGAAAACAGATCCAAATAATGCTATCTTACGTGGCTTAGGGGAGAACTTAACTA
ATCCAAACAATATGGATCCCTTTAGTGAATTTTTCAATCATTTAGGTGGTTACCCTGGTAATACCCCAGCTGGTAAGAAT
CGAGATCAAACACCTCCTACTCAAGCAGGCGGTGGCAACGGTGGTGGTCGATTCAATCAACCAAATGTGGGTCAAACCCA
AACAGTCCCACAACCAAATGGATTGCTGGAAGAATTTGGGATTAATGTTACTGAGATTGCACGACGTGGAGATATTGACC
CCGTTATCGGACGCGATCAAGAAATCACTCGGGTGATTGAAATTTTGAACCGTCGCACCAAAAACAACCCTGTTCTTATC
GGTGAGCCCGGTGTTGGTAAAACTGCAGTCGTTGAAGGACTAGCACAAAAAATTGTAGACGGGGACGTTCCACATAAACT
TCAAAACAAAGAAGTCATTCGATTAGACGTTGTCAGCCTTGTTCAAGGAACAGGAATCCGAGGTCAATTTGAAGAACGCA
TGCAAAAACTCATGGAAGAAATTCGGAACCGACGTGAAGTTATTCTCTTCATTGATGAAATTCATGAGATTGTCGGAGCT
GGTTCTGCAGGAGATGGAAACATGGATGCGGGCAATATTCTAAAACCCGCCCTCGCTCGTGGTGAAATGCAACTGGTCGG
TGCTACTACTTTAAATGAATACCGCATTATAGAAAAAGATGCAGCTCTTGAACGTCGGATGCAACCTGTAAAAGTTGACG
AACCAAGTGTTGAAGAAACAATCACTATCTTAAAAGGTATTCAGAATAAATACCAAGACTACCACCATGTAAAATATTCC
CCTGAGGCAATTGAAGCTGCGGCCGTATTATCCAACCGCTATATTCAAGACCGATTCTTACCTGATAAAGCGATTGATTT
GCTAGACGAAGCTGGATCAAAAATGAACTTAACCTTGAACTTCGTAGATCCTAAAGAAATTGACCAACGGTTAATTGATG
CCGAAAATCGTAAAGAACAAGCAACTCGTGATGAAGATTACGAAAAAGCTGCCTATTATCGTGACCAAATTGCTAAATAT
AAAGAAATGCAAAAGGCAACGATTAGTGAGGAGGATATTCCTCTCATTACCGAAAAAGAAATCGAAGCCATCATTGAACA
AAAAACAAATATCCCTGTTGGCGAGCTGAAAGAAAAAGAACAGTCTCAATTGATACATTTGGCAAGTGATCTCAAAGCGC
ATGTCATTGGACAAGACGATGCTGTTGATAAAATTGCAAAAGCAATCCGTCGCAATCGTGTAGGACTTGGAGCACCAAAT
CGTCCAATTGGTTCCTTCTTATTCGTAGGACCTACTGGCGTCGGTAAAACAGAATTATCAAAACAATTAGCCATTGAGCT
CTTCGGTTCAGCGGACAGCATGATTCGATTTGATATGTCTGAATATATGGAAAAACACGCAGTTGCAAAACTAGTCGGTG
CCCCTCCTGGATATGTGGGGTATGAAGAAGCTGGCCAACTAACAGAAAAAGTCCGTCGCAATCCATACTCACTCATTCTC
CTTGATGAAGTTGAAAAGGCGCATCCAGATGTGATGCACATGTTCCTACAAGTTCTTGATGACGGTCGACTGACAGATGG
ACAAGGGCGAACAGTCAGCTTCAAAGATACCATTATCATTATGACTTCAAATGCTGGTACAGGTAAGGTTGAGGCCAGCG
TGGGATTTGGAGCCGCTATGGAAGGTCGTACACAATCTGTTCTTGGCCAACTCGGTAATTTCTTCACTCCCGAATTCATG
AACCGCTTCGATGGAATTATTGAATTCCAACCACTTACAAAAGAAAATCTGCTCCAAATTGTCAGTCTCATGCTGGAAGA
CGTCAACCGTCGCTTATCTACAAACGGTATTCGACTACATGTGACCGATAAAGTAAAGGAAAAATTAGTTGATCTTGGTT
ACGATCCTAAAATGGGTGCACGTCCCCTTCGCAGGACCATTCAAGACCAAATTGAAGATGCCATTACCGATTTCTATTTA
GAGAATCCTAATGAGAAAGATTTACGAGCTGTCATGACCAATAAAGGCACCATCCAAATCAAAGCTCAACCGCCAAAAGA
AAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)

AAA lid domain (AAA_lid_9)

(296-394)

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-724)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.713

100

0.832
  clpE Streptococcus pneumoniae D39

82.713

100

0.832
  clpE Streptococcus pneumoniae R6

82.713

100

0.832
  clpE Streptococcus pneumoniae TIGR4

82.713

100

0.832
  clpE Streptococcus mutans UA159

83.087

99.599

0.828
  clpC Lactococcus lactis subsp. cremoris KW2

76.438

97.594

0.746
  clpC Bacillus subtilis subsp. subtilis str. 168

52.167

83.289

0.434
  clpC Streptococcus mutans UA159

47.235

84.626

0.4
  clpC Streptococcus pneumoniae Rx1

46.929

84.893

0.398
  clpC Streptococcus pneumoniae D39

46.929

84.893

0.398
  clpC Streptococcus pneumoniae TIGR4

46.929

84.893

0.398
  clpC Streptococcus thermophilus LMD-9

46.688

84.759

0.396
  clpC Streptococcus thermophilus LMG 18311

46.372

84.759

0.393
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.361

84.492

0.392