Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   MQE23_RS19510 Genome accession   NZ_CP094344
Coordinates   4309486..4310610 (+) Length   374 a.a.
NCBI ID   WP_029181796.1    Uniprot ID   A0A2N9B9L9
Organism   Streptomyces sp. HP-A2021     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4304486..4315610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MQE23_RS19495 (MQE23_19495) - 4305258..4306073 (+) 816 WP_037672020.1 hypothetical protein -
  MQE23_RS19500 (MQE23_19500) - 4306078..4307799 (-) 1722 WP_243379711.1 hypothetical protein -
  MQE23_RS19505 (MQE23_19505) radA 4307996..4309405 (+) 1410 WP_020275630.1 DNA repair protein RadA Machinery gene
  MQE23_RS19510 (MQE23_19510) disA 4309486..4310610 (+) 1125 WP_029181796.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  MQE23_RS19515 (MQE23_19515) - 4310723..4311598 (-) 876 WP_082320029.1 hypothetical protein -
  MQE23_RS19520 (MQE23_19520) - 4311774..4312415 (+) 642 WP_243379712.1 phosphatase PAP2 family protein -
  MQE23_RS19525 (MQE23_19525) - 4312536..4313192 (-) 657 WP_020275627.1 response regulator transcription factor -
  MQE23_RS19530 (MQE23_19530) - 4313189..4314796 (-) 1608 WP_243379713.1 histidine kinase -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 39992.70 Da        Isoelectric Point: 4.9201

>NTDB_id=577528 MQE23_RS19510 WP_029181796.1 4309486..4310610(+) (disA) [Streptomyces sp. HP-A2021]
MAANDRASAPGKSGGSAGTDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDKTVEALCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=577528 MQE23_RS19510 WP_029181796.1 4309486..4310610(+) (disA) [Streptomyces sp. HP-A2021]
GTGGCAGCCAACGACCGGGCATCAGCTCCCGGAAAGTCCGGCGGGAGTGCCGGTACCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCACCCGGCACCGCCCTGCGTGACGGCCTGGAGCGCGTGCTCCGCGGCAACACCGGCGGACTCATCGTCC
TCGGCTCCGACAAGACGGTCGAGGCGCTCTGTACCGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGTCTGCGC
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTGTCCTCGGACCTGTCGAAGATCCTGCGCGCGGGCGTGCAGCTGGTCCC
GGACCCGACGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACCGCGGACCGCGTCAGCAAGCAGGTCGGCTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCCCTGTACGTGGACGGCCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGTGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTCTCGGCGGTCGCCCAGCGCCTGGAGATGGTGCGCCGCATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGCCGGCTGCTGGCCCTCCAGCTCGACGAGCTGATCGCC
GGCGTGGAGCCCGAGCGCGAGCTGGTCGTCCGGGACTACGTGCCCGAGCCCACCGCCAAGCGCTCCCGCACGGTCGACGA
GGCGCTGGCCGAGCTGGACGCCCTCACCCACGCCGAGCTTCTCGAACTGCCCACGGTGGCCCGGGCGTTGGGCTACACCG
GCTCGCCCGAGACGCTGGACTCGGCGGTGTCTCCGCGTGGCTTCCGCCTGCTCGCCAAGGTGCCCCGGCTCCCCGGCGCG
ATCATCGACCGCCTGGTCGAGCACTTCGGCGGCCTCCAGAAGCTGCTCGCCGCGAGCGTCGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCCCGGGCGCGCAGCGTCCGGGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2N9B9L9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.706

96.524

0.441