Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   MP387_RS07730 Genome accession   NZ_CP094226
Coordinates   1591737..1593842 (-) Length   701 a.a.
NCBI ID   WP_242746082.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1586737..1598842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS07715 (MP387_07715) - 1587855..1589465 (-) 1611 WP_242746078.1 alpha-glucosidase -
  MP387_RS07720 (MP387_07720) - 1589618..1591102 (+) 1485 WP_242746080.1 DUF1846 domain-containing protein -
  MP387_RS07725 (MP387_07725) - 1591194..1591676 (+) 483 WP_000032556.1 S-ribosylhomocysteine lyase -
  MP387_RS07730 (MP387_07730) clpE 1591737..1593842 (-) 2106 WP_242746082.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  MP387_RS07735 (MP387_07735) pflB 1594261..1596576 (-) 2316 WP_242746084.1 formate C-acetyltransferase -
  MP387_RS07740 (MP387_07740) dinB 1596809..1597870 (+) 1062 WP_242746092.1 DNA polymerase IV -
  MP387_RS07745 (MP387_07745) - 1597905..1598750 (-) 846 WP_242746095.1 undecaprenyl-diphosphate phosphatase -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77535.31 Da        Isoelectric Point: 4.6915

>NTDB_id=577252 MP387_RS07730 WP_242746082.1 1591737..1593842(-) (clpE) [Streptococcus oralis strain 1648]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRCYLINGREVTPEEFAHYRATGQLPGNAESDMQMQQHASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSIGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFEILQGIRDLYQQHHNVILPDEVLKAAVDYSIQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKVENHTEDMKVTASINDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLAEVNQTLAKKDIDLEVS
QAAKDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=577252 MP387_RS07730 WP_242746082.1 1591737..1593842(-) (clpE) [Streptococcus oralis strain 1648]
ATGAACAACAACTTTAATAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAACCGTTGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATATGCAAATGCAACAACACGCTTCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGTAACTTGACCGCAGAAGCTCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACGAAAAATAATCCTGTTCTGGTCGGAGATGCAGGTGTTGGTAAGACCGCAGTTGTCGAAGGCC
TAGCACAAGCAATTGTGAACGGAGATGTTCCAGCTGCTATTAAGAACAAGGAAATCATTTCCATTGATATTTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAACCTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATCCTTGGCGCTGGCTCAATCGGAGGAGACAGTGGTTCTAAAGGGCTTGCGG
ACATTCTCAAGCCAGCTCTCTCTCGTGGTGAATTGACCGTTATTGGAGCGACAACTCAAGACGAATACCGTAACACCATC
TTGAAAAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTGAAATCCT
TCAAGGGATTCGTGACCTCTATCAACAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCAGTGGATTATT
CTATCCAATACATTCCACAACGCAGCTTGCCAGATAAGGCTATTGACCTTGTAGACGTAACGGCTGCTCACTTGGCAGCT
CAACATCCTGTAACAGATGTGCATGCTGTTGAACGGGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGATTTTGAAGCAGCTCTCAATGCCAAAACACGTATTGCAGAATTAGAGAAAAAAGTCGAAAACCACACAGAAGACA
TGAAAGTGACTGCAAGCATCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTTTCACAAATGGGAGCA
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGGAACACAAGGTTATCGGCCAAGACAAGGCGGTTGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGCAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGTCCAA
CTGGGGTTGGTAAGACAGAACTTGCTAAGCAATTAGCGCTCGATATGTTTGGTACTAAAGATGCGATCATCCGCTTGGAT
ATGTCTGAATACAGTGACCGCACAGCCGTATCTAAATTAATCGGTACAACAGCAGGTTATGTTGGGTATGATGACAATAG
CAATACCTTGACAGAACGTGTTCGCCGCAATCCTTATTCTATCATTCTCTTGGACGAAATTGAAAAGGCTGATCCTCAAG
TAATCACCCTTCTCCTCCAAGTATTGGATGACGGTCGTTTGACTGATGGTCAAGGAAATACAGTGAACTTCAAGAACACG
GTCATTATCGCGACATCAAATGCTGGATTTGGTTATGAAGCCAACTTGACAGAAGATGCGGACAAACCAGAGTTGATGGA
TCGTTTGAAACCATTCTTCCGTCCAGAATTCCTCAACCGCTTTAACGCAGTTATCGAGTTTTCACACTTGAACAAGGAAG
ATCTTTCTAAGATTGTGGACTTGATGTTGGCGGAAGTCAACCAAACTTTGGCTAAGAAAGACATTGATTTGGAAGTCAGC
CAAGCAGCTAAGGACTTTATCACAGAAGAAGGCTATGACGAAGTCATGGGTGTTCGTCCTCTCCGTCGCGTGGTTGAACA
ACAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATCTAGATGCTAAACATTTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA lid domain (AAA_lid_9)

(259-354)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

50.621

91.869

0.465
  clpC Lactococcus lactis subsp. cremoris KW2

50.156

91.298

0.458
  clpE Streptococcus pneumoniae TIGR4

48.896

90.442

0.442
  clpE Streptococcus pneumoniae Rx1

48.657

90.3

0.439
  clpE Streptococcus pneumoniae D39

48.657

90.3

0.439
  clpE Streptococcus pneumoniae R6

48.657

90.3

0.439
  clpC Bacillus subtilis subsp. subtilis str. 168

45.146

92.582

0.418
  clpC Streptococcus pneumoniae D39

43.109

89.016

0.384
  clpC Streptococcus pneumoniae Rx1

43.109

89.016

0.384
  clpC Streptococcus pneumoniae TIGR4

42.949

89.016

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.875

91.298

0.382
  clpC Streptococcus thermophilus LMD-9

43.112

88.017

0.379
  clpC Streptococcus thermophilus LMG 18311

42.95

88.017

0.378
  clpC Streptococcus mutans UA159

42.071

88.16

0.371