Detailed information NTG0577124

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KQU62_RS08145
• Genome accession: NZ_CP076660
• Coordinates: 1645379..1646422 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SG511 Berlin
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1640379..1651422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KQU62_RS08115 (KQU62_08115)	-	1640799..1642055 (-)	1257	WP_001793983.1	aminopeptidase	-
KQU62_RS08120 (KQU62_08120)	-	1642058..1642258 (-)	201	WP_000180460.1	DUF1128 family protein	-
KQU62_RS08125 (KQU62_08125)	-	1642405..1642869 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
KQU62_RS08130 (KQU62_08130)	-	1642876..1643151 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KQU62_RS08135 (KQU62_08135)	-	1643430..1644647 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
KQU62_RS08140 (KQU62_08140)	vraR	1644760..1645389 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KQU62_RS08145 (KQU62_08145)	vraS	1645379..1646422 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KQU62_RS08150 (KQU62_08150)	liaF	1646419..1647120 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KQU62_RS08155 (KQU62_08155)	-	1647135..1647521 (-)	387	WP_001110178.1	hypothetical protein	-
KQU62_RS08160 (KQU62_08160)	map	1647738..1648496 (-)	759	WP_123090064.1	type I methionyl aminopeptidase	-
KQU62_RS08165 (KQU62_08165)	-	1649081..1650067 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
KQU62_RS08170 (KQU62_08170)	-	1650256..1650669 (-)	414	WP_001643743.1	hypothetical protein	-
KQU62_RS08175 (KQU62_08175)	-	1650698..1650808 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=577124 KQU62_RS08145 WP_001017131.1 1645379..1646422(-) (vraS) [Staphylococcus aureus strain SG511 Berlin]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=577124 KQU62_RS08145 WP_001017131.1 1645379..1646422(-) (vraS) [Staphylococcus aureus strain SG511 Berlin]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1