Detailed information NTG0576590

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPG52_RS03010
• Genome accession: NZ_CP094157
• Coordinates: 638551..640920 (-)
• Length: 789 a.a.
• NCBI ID: WP_342371208.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe0021
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 633551..645920

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPG52_RS02985 (MPG52_02985)	-	633560..634822 (-)	1263	WP_180514893.1	P-type conjugative transfer protein TrbL	-
MPG52_RS02990 (MPG52_02990)	-	634824..635102 (-)	279	WP_120873246.1	hypothetical protein	-
MPG52_RS02995 (MPG52_02995)	-	635151..635593 (-)	443	Protein_591	hypothetical protein	-
MPG52_RS07780	-	635589..636398 (-)	810	WP_342371077.1	VirB8/TrbF family protein	-
MPG52_RS03005 (MPG52_03005)	-	636515..638548 (-)	2034	Protein_593	type IA DNA topoisomerase	-
MPG52_RS03010 (MPG52_03010)	comB4	638551..640920 (-)	2370	WP_342371208.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPG52_RS03015 (MPG52_03015)	comB3	640967..641233 (-)	267	WP_064431320.1	hypothetical protein	Machinery gene
MPG52_RS03020 (MPG52_03020)	-	641234..641536 (-)	303	WP_108538717.1	virB2 type IV secretion protein	-
MPG52_RS03025 (MPG52_03025)	-	641533..643056 (-)	1524	WP_245077152.1	hypothetical protein	-
MPG52_RS03030 (MPG52_03030)	-	643063..643356 (-)	294	WP_025276172.1	hypothetical protein	-
MPG52_RS03035 (MPG52_03035)	-	643376..644051 (-)	676	Protein_599	hypothetical protein	-
MPG52_RS03040 (MPG52_03040)	-	644045..644584 (+)	540	Protein_600	DNA adenine methylase	-
MPG52_RS03045 (MPG52_03045)	-	644586..645210 (+)	625	Protein_601	GIY-YIG nuclease family protein	-
MPG52_RS03050 (MPG52_03050)	-	645307..645789 (+)	483	Protein_602	DNA cytosine methyltransferase	-

Sequence

Protein

• Length: 789 a.a.
• Molecular weight: 91235.60 Da
• Isoelectric Point: 7.1472

>NTDB_id=576590 MPG52_RS03010 WP_342371208.1 638551..640920(-) (comB4) [Helicobacter pylori strain Hpfe0021]
MKEETNIVGIYNEHYLLSEKSNLVGTLKLEGISYLSLDDKEIAQKFNERILALNEIVDGVHFKIVARRRKIFMHHEYTQE
EISNPFALEVINLWEQGVEDVYQNFYYLIFETKNDSIKGYLERFKKKITTNELENIQENDKQDEIKYQENYFIGFDNFNL
LDKSKILDSIINNVKNMLSGLFVEKIDANSLLNFYAEYINGVPSEYTFARGRLHDGMINSDVHFKKDFFTHIHNSKEIFK
RFISIKTYDIDKIVSTALSSVLHLSLEFDVILNIDNIPKAKAEKRIETKRKRANKSIRVEIDELNDMVKTDRVLMQEISL
NILVHAKTKTDLDSACIEITNLLKQKGIISTQESIGMLPMFFSFFPNCNRLNFRKRLLSSQNIASLIVLEKQNCGFSRNS
WGDRHLTIFRNQDKSPYLFNFHAYEAKRKNDMVSGHTIIFGGTGAGKTTLIEFLITNCFKYEDLSILALDRNNGMRVMTE
FLDGQYNDSNDFYINPFSLKDTSANCTFLVSWLAFMLNIDEDTKDEKEKKTLSALSKTIRVCYNNITKQGGAIFKLRDFK
DTLERDYLDSKDILEKESSKDLYKHSTDCLDFAKKLSVIDMDALSSSKKDFNLAVLYLFYKVMNRAKLENKPFYIFIDEA
KSVIENPIMLAKIKDTLAQARKLNGVLTLAFQDINQLDGIEGAKSIIENAAQVILYPTNNFEKLESYGILLSPIEKSFLN
KTPLNARQVLVKNLLTQSSVFLEINLEKLNSTSKKFLRAYNSSASSVFELETLKKDNPKDYKEIYLTKE

Nucleotide

• Length: 2370 bp

>NTDB_id=576590 MPG52_RS03010 WP_342371208.1 638551..640920(-) (comB4) [Helicobacter pylori strain Hpfe0021]
ATGAAAGAAGAAACTAACATTGTTGGCATTTATAATGAGCATTATCTTTTAAGTGAAAAATCAAACCTTGTAGGCACTCT
TAAATTAGAGGGAATTTCTTATTTGTCTTTAGATGACAAAGAAATAGCGCAAAAATTCAATGAACGCATTTTAGCTCTTA
ATGAGATTGTAGATGGAGTGCATTTTAAAATTGTAGCTAGAAGGCGTAAGATTTTCATGCACCATGAATATACTCAAGAG
GAGATAAGCAATCCTTTTGCATTAGAGGTTATCAATTTATGGGAGCAGGGGGTTGAGGATGTTTATCAAAATTTCTACTA
CTTAATTTTTGAAACTAAGAATGATAGCATTAAAGGTTATTTGGAACGATTTAAGAAAAAAATCACTACCAATGAATTAG
AAAATATTCAAGAAAATGATAAACAAGATGAAATTAAATATCAAGAAAACTATTTCATAGGCTTTGATAATTTTAATCTA
TTAGATAAATCTAAAATATTAGACAGCATTATCAATAATGTTAAAAACATGCTTTCTGGCTTGTTTGTAGAAAAAATAGA
TGCCAATAGTTTGCTTAATTTTTATGCGGAATATATCAATGGTGTTCCTAGTGAATACACTTTCGCTAGAGGTCGTTTGC
ATGATGGCATGATCAATTCTGATGTGCATTTTAAAAAAGATTTTTTCACTCACATTCATAATAGTAAAGAGATTTTCAAG
CGTTTCATCAGCATTAAGACTTATGATATAGACAAAATTGTCAGCACTGCTCTTTCTTCAGTGTTGCATTTATCTTTAGA
ATTTGATGTGATTTTAAACATTGACAATATTCCTAAAGCAAAGGCTGAAAAAAGGATTGAAACTAAAAGAAAAAGAGCGA
ATAAGAGCATTAGAGTTGAAATTGATGAATTGAATGACATGGTTAAAACAGACAGAGTTTTAATGCAAGAGATTTCTTTA
AACATTTTAGTTCATGCCAAAACTAAAACCGATTTAGATAGTGCTTGTATAGAAATTACCAACTTGCTTAAACAAAAAGG
TATTATAAGCACACAAGAGAGTATTGGCATGTTGCCTATGTTTTTTAGCTTTTTCCCCAATTGTAATCGCTTGAATTTTA
GAAAGCGTTTGTTGTCTAGTCAAAATATTGCTTCTTTAATCGTATTGGAAAAACAAAATTGTGGTTTTTCTAGAAATTCA
TGGGGTGATCGCCATTTAACTATTTTTAGAAACCAAGACAAATCGCCTTATTTATTCAATTTCCATGCTTATGAGGCAAA
AAGAAAAAATGATATGGTATCAGGGCATACCATCATCTTTGGTGGCACAGGGGCTGGTAAAACCACTTTAATTGAATTTT
TAATCACCAATTGTTTTAAGTATGAAGATTTAAGTATTTTGGCTTTAGACAGAAATAATGGCATGCGTGTGATGACTGAG
TTTTTAGATGGTCAATACAACGATAGCAATGATTTTTACATTAATCCGTTTTCTTTAAAAGATACAAGTGCTAACTGCAC
CTTTTTAGTGAGTTGGTTGGCATTCATGCTCAATATTGATGAAGATACTAAAGATGAAAAAGAAAAAAAGACTTTAAGCG
CTTTATCCAAAACAATCAGAGTTTGCTATAACAATATCACAAAACAAGGGGGTGCTATTTTTAAGTTAAGAGATTTTAAA
GACACGCTAGAAAGAGACTATTTAGATAGCAAAGACATTTTAGAAAAAGAGAGCTCAAAAGACTTATACAAGCATTCTAC
TGATTGTTTAGACTTTGCTAAAAAGCTTTCTGTTATTGATATGGATGCTCTTTCTAGTAGTAAAAAAGATTTCAACTTGG
CAGTGCTATACCTATTCTACAAAGTCATGAATAGAGCTAAATTAGAAAACAAGCCTTTTTATATCTTCATTGATGAAGCA
AAATCTGTTATTGAAAATCCCATCATGTTAGCTAAAATCAAAGACACACTCGCTCAAGCTAGAAAACTCAATGGGGTTTT
AACTTTAGCCTTTCAAGACATTAACCAACTTGATGGCATAGAGGGAGCAAAGTCCATTATTGAAAACGCCGCTCAAGTCA
TACTCTATCCTACAAACAATTTTGAGAAATTAGAGAGCTATGGCATTTTATTAAGTCCTATTGAAAAATCCTTTTTAAAC
AAAACGCCGTTAAACGCTAGGCAAGTATTAGTGAAAAACCTTCTCACTCAATCTAGTGTATTTTTAGAAATCAATTTAGA
AAAGCTAAACAGCACCAGTAAAAAATTTTTAAGAGCGTATAACTCTAGCGCGTCTAGCGTTTTTGAACTGGAAACGCTTA
AAAAGGATAATCCAAAGGACTATAAAGAAATTTACTTGACAAAGGAGTAG

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (176-374)

• Helicase HerA, central domain (DUF87) (430-472)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	35.849	100	0.361