Detailed information NTG0576362

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPF84_RS02465
• Genome accession: NZ_CP094149
• Coordinates: 503966..506542 (+)
• Length: 858 a.a.
• NCBI ID: WP_245086302.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe023
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 498966..511542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPF84_RS02435 (MPF84_02435)	-	501102..501815 (+)	714	WP_245086293.1	dynamin family protein	-
MPF84_RS02440 (MPF84_02440)	-	501793..502581 (+)	789	WP_245086296.1	integrase	-
MPF84_RS02445 (MPF84_02445)	-	502685..503164 (+)	480	WP_245086299.1	hypothetical protein	-
MPF84_RS02450 (MPF84_02450)	comB2	503161..503445 (+)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
MPF84_RS02455 (MPF84_02455)	comB3	503456..503719 (+)	264	WP_001177712.1	hypothetical protein	Machinery gene
MPF84_RS02460 (MPF84_02460)	-	503730..503966 (+)	237	WP_180386948.1	hypothetical protein	-
MPF84_RS02465 (MPF84_02465)	comB4	503966..506542 (+)	2577	WP_245086302.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPF84_RS02470 (MPF84_02470)	-	506539..506679 (+)	141	WP_015643441.1	hypothetical protein	-
MPF84_RS02475 (MPF84_02475)	-	506672..507811 (+)	1140	WP_245052287.1	VirB8/TrbF family protein	-
MPF84_RS02480 (MPF84_02480)	-	507808..509472 (+)	1665	WP_180618312.1	TrbG/VirB9 family P-type conjugative transfer protein	-
MPF84_RS02485 (MPF84_02485)	comB10	509469..510668 (+)	1200	WP_245086306.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98900.92 Da
• Isoelectric Point: 8.8643

>NTDB_id=576362 MPF84_RS02465 WP_245086302.1 503966..506542(+) (comB4) [Helicobacter pylori strain Hpfe023]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAITSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSKKDKKNKFKKKITFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRYQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNTNILDSSFEYYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVFK

Nucleotide

• Length: 2577 bp

>NTDB_id=576362 MPF84_RS02465 WP_245086302.1 503966..506542(+) (comB4) [Helicobacter pylori strain Hpfe023]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTACGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATACATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTACAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAACCCTAGAATGAGATATCAAACTTCCCAAGTCATAGCATCTTTGATTTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTCGCACGAGTGGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGCAAAACCACACTCATTAGCTATTTGATGATGAGCGCTTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAATGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTG
TCAATGCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAATACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCCTACTATGTCTTTCATAAGATGATTGACAGAGCCTTAAAAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGTTTAAATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.024	97.902	0.46