Detailed information NTG0057634

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: JP49775_RS12770
• Genome accession: NZ_AP017922
• Coordinates: 2538704..2540812 (+)
• Length: 702 a.a.
• NCBI ID: WP_029549964.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain JP02758
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2533704..2545812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JP49775_RS12745 (JP02758_2368)	-	2533724..2533942 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
JP49775_RS12750 (JP02758_2369)	-	2534331..2534762 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
JP49775_RS12755 (JP02758_2370)	-	2534902..2536182 (-)	1281	WP_029549965.1	hydroxymethylglutaryl-CoA reductase, degradative	-
JP49775_RS12760 (JP02758_2371)	-	2536437..2537603 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
JP49775_RS12765 (JP02758_2372)	-	2537774..2538295 (-)	522	WP_000384652.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
JP49775_RS12770 (JP02758_2373)	clpE	2538704..2540812 (+)	2109	WP_029549964.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
JP49775_RS12775 (JP02758_2374)	-	2540879..2541049 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
JP49775_RS12780 (JP02758_2375)	feoB	2541062..2543056 (-)	1995	WP_029549963.1	ferrous iron transport protein B	-
JP49775_RS12785 (JP02758_2376)	-	2543068..2543295 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77966.36 Da
• Isoelectric Point: 4.6255

>NTDB_id=57634 JP49775_RS12770 WP_029549964.1 2538704..2540812(+) (clpE) [Staphylococcus aureus strain JP02758]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=57634 JP49775_RS12770 WP_029549964.1 2538704..2540812(+) (clpE) [Staphylococcus aureus strain JP02758]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGCCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTGCTTGTTAATGAACCAAGCGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCAGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGCGCTGGGTTTGATGACGGCAACCGTCCAATTGGTAGTTTCC
TATTTGTCGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTTATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTATTACTACAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGCAATGACACTGAAGAAAAAGACATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGAACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.678	91.595	0.446
clpE	Streptococcus pneumoniae Rx1	48.136	87.892	0.423
clpE	Streptococcus pneumoniae D39	48.136	87.892	0.423
clpE	Streptococcus pneumoniae R6	48.136	87.892	0.423
clpE	Streptococcus pneumoniae TIGR4	48.136	87.892	0.423
clpC	Lactococcus lactis subsp. cremoris KW2	46.519	90.028	0.419
clpC	Bacillus subtilis subsp. subtilis str. 168	44.564	93.02	0.415
clpC	Streptococcus thermophilus LMD-9	44.234	90.171	0.399
clpC	Streptococcus thermophilus LMG 18311	43.918	90.171	0.396
clpC	Streptococcus pneumoniae TIGR4	43.851	88.034	0.386
clpC	Streptococcus pneumoniae Rx1	43.851	88.034	0.386
clpC	Streptococcus pneumoniae D39	43.851	88.034	0.386
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.45	0.382