Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   MPG21_RS06000 Genome accession   NZ_CP094133
Coordinates   1255875..1257107 (+) Length   410 a.a.
NCBI ID   WP_245025042.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe049     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1250875..1262107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG21_RS05985 (MPG21_05985) - 1251288..1253222 (+) 1935 WP_245026085.1 type IA DNA topoisomerase -
  MPG21_RS07795 - 1253222..1253350 (+) 129 WP_001185489.1 hypothetical protein -
  MPG21_RS05990 (MPG21_05990) - 1253352..1254335 (+) 984 WP_180478804.1 virB8 family protein -
  MPG21_RS05995 (MPG21_05995) - 1254335..1255878 (+) 1544 Protein_1177 TrbG/VirB9 family P-type conjugative transfer protein -
  MPG21_RS06000 (MPG21_06000) comB10 1255875..1257107 (+) 1233 WP_245025042.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG21_RS06005 (MPG21_06005) - 1257177..1257470 (+) 294 WP_000671327.1 hypothetical protein -
  MPG21_RS06010 (MPG21_06010) - 1257463..1257726 (+) 264 WP_245025044.1 hypothetical protein -
  MPG21_RS06015 (MPG21_06015) - 1257723..1258022 (+) 300 WP_231202443.1 hypothetical protein -
  MPG21_RS06020 (MPG21_06020) - 1258022..1258962 (+) 941 Protein_1182 ATPase, T2SS/T4P/T4SS family -
  MPG21_RS06025 (MPG21_06025) - 1258959..1259414 (+) 456 WP_245025046.1 mobilization protein -
  MPG21_RS06030 (MPG21_06030) - 1259411..1259701 (+) 291 WP_050850784.1 hypothetical protein -
  MPG21_RS06035 (MPG21_06035) - 1259702..1260259 (+) 558 WP_245025048.1 hypothetical protein -
  MPG21_RS06040 (MPG21_06040) - 1260260..1261207 (+) 948 WP_245025050.1 type IV secretory system conjugative DNA transfer family protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 46340.38 Da        Isoelectric Point: 10.0008

>NTDB_id=575820 MPG21_RS06000 WP_245025042.1 1255875..1257107(+) (comB10) [Helicobacter pylori strain Hpfe049]
MKKLLLLLDHKIIKIGLIIVIVLVGFFLFYEQEIKEKAVNVSQGKFPTSSYLFQAYEGIKNKIDAINEVKPNDETKSVNE
NIEKTQKDLDDFNALVQKLPNLPKDFNKTLIKPQNPSFNYNTANEEEKTRLVILASRISSQKEMQPPTSIKNSVSNTKSK
EKQELEKEYGSSGFKNFKRKNVASSENKLLRTITADRMIPAILITPISSEIGGSKIVAQVESDIYATMGRAVLIPKGSRA
IGYYNSNNKIGEYRLEIAWNRIITPQGVNIILSDAKGSDVKGYNGMIGTLHNKYWERYGIPLSLSTLSNGLLIGLTSGLT
EAMKNKKGGFNQNYFGDYMMQMTRQTGISLNNIIAQIMREQIRIKPIITIREGSHIFISPNTDIWFPIPKNNEVLAKFFN
EEKEQNNDTK

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=575820 MPG21_RS06000 WP_245025042.1 1255875..1257107(+) (comB10) [Helicobacter pylori strain Hpfe049]
ATGAAAAAACTTCTTTTACTTTTAGATCATAAAATCATAAAAATTGGCTTAATTATTGTGATTGTATTAGTTGGTTTTTT
TCTTTTTTACGAACAAGAAATCAAAGAAAAAGCTGTTAATGTTTCTCAAGGTAAATTCCCTACTTCATCTTATTTGTTTC
AAGCTTACGAAGGCATTAAAAATAAAATAGATGCTATCAATGAAGTGAAACCAAACGATGAAACTAAAAGCGTTAATGAG
AATATAGAAAAAACACAAAAAGATTTAGATGACTTTAATGCACTAGTGCAAAAATTACCAAATTTGCCTAAGGATTTTAA
TAAAACGCTTATTAAACCACAAAATCCATCCTTCAACTACAATACCGCTAACGAAGAAGAAAAAACCCGCCTTGTGATTT
TAGCGTCTCGTATTAGCAGCCAAAAAGAAATGCAGCCTCCAACCTCTATAAAAAATAGTGTTTCTAATACAAAATCTAAA
GAAAAACAAGAACTTGAAAAAGAATACGGCTCTAGCGGTTTTAAAAATTTTAAAAGAAAAAATGTAGCGAGCAGTGAAAA
CAAACTTTTGAGAACGATTACAGCTGACAGAATGATCCCAGCCATTCTGATCACTCCCATTAGTAGTGAAATAGGGGGGA
GTAAGATAGTCGCTCAAGTGGAGAGTGATATATACGCAACGATGGGTAGAGCGGTTTTAATCCCTAAAGGGAGTAGAGCT
ATAGGCTATTACAACTCTAATAACAAAATAGGAGAATACCGATTAGAAATTGCTTGGAATAGGATAATCACGCCACAAGG
GGTCAATATCATACTAAGCGATGCTAAGGGATCTGATGTCAAGGGCTATAACGGTATGATAGGCACACTCCATAACAAAT
ATTGGGAACGCTATGGTATTCCTTTATCCTTAAGCACCTTGTCAAATGGGCTACTCATAGGTCTTACTAGCGGTCTTACC
GAAGCGATGAAAAACAAAAAGGGTGGCTTTAACCAAAACTATTTTGGAGATTACATGATGCAAATGACGAGGCAAACTGG
TATCAGCCTAAATAATATTATCGCTCAAATCATGCGAGAGCAAATCAGGATTAAGCCCATTATCACTATTAGAGAAGGAA
GCCATATTTTTATTAGTCCTAATACGGATATTTGGTTTCCTATCCCTAAAAACAATGAAGTCTTAGCGAAATTTTTTAAT
GAAGAAAAGGAGCAAAACAATGATACAAAATAG

Domains

Predicted by InterProScan.

Bacterial conjugation TrbI-like protein (TrbI)

(192-386)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

56.458

66.098

0.373