NTDB

Overview

Name	comGC/cglC	Type	Machinery gene
Locus tag	KPU58_RS08225	Genome accession	NZ_CP076498
Coordinates	1662371..1662646 (+)	Length	91 a.a.
NCBI ID	WP_002356991.1	Uniprot ID	A0A1B4XPV0
Organism	Enterococcus faecalis strain UAMS_EL53
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1657371..1667646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KPU58_RS08205 (KPU58_08160)	rlmN	1657467..1658540 (+)	1074	WP_002356987.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
KPU58_RS08210 (KPU58_08165)	-	1658831..1660159 (+)	1329	WP_002362058.1	amino acid permease	-
KPU58_RS08215 (KPU58_08170)	comGA	1660400..1661368 (+)	969	WP_002364362.1	competence type IV pilus ATPase ComGA	-
KPU58_RS08220 (KPU58_08175)	comGB	1661325..1662371 (+)	1047	WP_002356990.1	competence type IV pilus assembly protein ComGB	-
KPU58_RS08225 (KPU58_08180)	comGC/cglC	1662371..1662646 (+)	276	WP_002356991.1	competence type IV pilus major pilin ComGC	Machinery gene
KPU58_RS08230 (KPU58_08185)	comGD	1662643..1663089 (+)	447	WP_002379576.1	competence type IV pilus minor pilin ComGD	-
KPU58_RS08235 (KPU58_08190)	-	1663055..1663381 (+)	327	WP_002393943.1	type II secretion system protein	-
KPU58_RS08240 (KPU58_08195)	comGF	1663371..1663805 (+)	435	WP_002357060.1	competence type IV pilus minor pilin ComGF	-
KPU58_RS08245 (KPU58_08200)	-	1663907..1665080 (+)	1174	Protein_1603	IS256-like element IS256 family transposase	-
KPU58_RS08250 (KPU58_08205)	comGG	1665138..1665491 (+)	354	WP_002357061.1	competence type IV pilus minor pilin ComGG	-
KPU58_RS08255 (KPU58_08210)	-	1665620..1666627 (+)	1008	WP_002357063.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

Download Length: 91 a.a. Molecular weight: 10464.41 Da Isoelectric Point: 9.3192

                                >NTDB_id=575797 KPU58_RS08225 WP_002356991.1 1662371..1662646(+) (comGC/cglC) [Enterococcus faecalis strain UAMS_EL53]

MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK

EQLDKYTAEKQ

Nucleotide

Download Length: 276 bp

                                >NTDB_id=575797 KPU58_RS08225 WP_002356991.1 1662371..1662646(+) (comGC/cglC) [Enterococcus faecalis strain UAMS_EL53]

ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT

ACTTTTTGTCCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT

CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA

GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A1B4XPV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGC/cglC	Streptococcus pneumoniae Rx1	63.095	92.308	0.582
comGC/cglC	Streptococcus pneumoniae D39	63.095	92.308	0.582
comGC/cglC	Streptococcus pneumoniae R6	63.095	92.308	0.582
comGC/cglC	Streptococcus pneumoniae TIGR4	63.095	92.308	0.582
comGC/cglC	Streptococcus mitis NCTC 12261	61.905	92.308	0.571
comGC/cglC	Streptococcus mitis SK321	61.176	93.407	0.571
comGC	Lactococcus lactis subsp. cremoris KW2	58.14	94.505	0.549
comYC	Streptococcus gordonii str. Challis substr. CH1	56.322	95.604	0.538
comYC	Streptococcus suis isolate S10	52.326	94.505	0.495
comYC	Streptococcus mutans UA159	57.692	85.714	0.495
comYC	Streptococcus mutans UA140	57.692	85.714	0.495
comGC	Latilactobacillus sakei subsp. sakei 23K	46.154	100	0.462
comGC	Staphylococcus aureus MW2	46.835	86.813	0.407
comGC	Staphylococcus aureus N315	46.835	86.813	0.407
comGC	Bacillus subtilis subsp. subtilis str. 168	48.649	81.319	0.396

Detailed information NTG0575797