Detailed information NTG0057530

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: I653_RS12190
• Genome accession: NC_020832
• Coordinates: 2452518..2454848 (-)
• Length: 776 a.a.
• NCBI ID: WP_041517945.1
• Uniprot ID: -
• Organism: Bacillus subtilis subsp. subtilis str. BAB-1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2447518..2459848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I653_RS12160 (I653_12280)	yqxA	2447857..2448195 (-)	339	WP_014477382.1	YqxA family protein	-
I653_RS12165 (I653_12285)	spoIIP	2448212..2449417 (-)	1206	WP_015384129.1	spore autolysin SpoIIP	-
I653_RS12170 (I653_12290)	gpr	2449480..2450586 (-)	1107	WP_014480309.1	GPR endopeptidase	-
I653_RS12175 (I653_12295)	rpsT	2450790..2451056 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
I653_RS12180 (I653_12300)	holA	2451071..2452114 (-)	1044	WP_015384130.1	DNA polymerase III subunit delta	-
I653_RS21035	-	2452154..2452303 (-)	150	WP_003229985.1	hypothetical protein	-
I653_RS20570 (I653_12305)	yqzM	2452344..2452478 (+)	135	WP_003229983.1	YqzM family protein	-
I653_RS12190 (I653_12310)	comEC	2452518..2454848 (-)	2331	WP_041517945.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I653_RS12195 (I653_12315)	comEB	2454852..2455421 (-)	570	WP_003229978.1	ComE operon protein 2	-
I653_RS12200 (I653_12320)	comEA	2455488..2456105 (-)	618	WP_015384132.1	competence protein ComEA	Machinery gene
I653_RS12205 (I653_12325)	comER	2456189..2457010 (+)	822	WP_004398597.1	late competence protein ComER	-
I653_RS12210 (I653_12330)	yqeM	2457076..2457819 (-)	744	WP_015384134.1	class I SAM-dependent methyltransferase	-
I653_RS12215 (I653_12335)	rsfS	2457816..2458172 (-)	357	WP_014480315.1	ribosome silencing factor	-
I653_RS12220 (I653_12340)	yqeK	2458190..2458750 (-)	561	WP_015483448.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
I653_RS12225 (I653_12345)	nadD	2458740..2459309 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
I653_RS12230 (I653_12350)	yhbY	2459321..2459611 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86647.97 Da
• Isoelectric Point: 6.8607

>NTDB_id=57530 I653_RS12190 WP_041517945.1 2452518..2454848(-) (comEC) [Bacillus subtilis subsp. subtilis str. BAB-1]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDNIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAASSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHKFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVTILLLLMAIEKRSLSQLMVTGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKYHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFTQQLQPETAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRGGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=57530 I653_RS12190 WP_041517945.1 2452518..2454848(-) (comEC) [Bacillus subtilis subsp. subtilis str. BAB-1]
ATGCGTAATTCGCGATTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACTTATCAATTC
AAGGCAGTGATTGACAATATTCCTAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAAGATGAAGTGCTTACTGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGGCTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATACGCCTTGGTATAACAAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTTCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATAAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCTGATGTTGATGTATTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCCTCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACTGGAGGC
ATTTGCTGCACGGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGTATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
GCACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCACCCAACAGCTTCAGCCGGAAACGGCCATTATCTCAGCTGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGGTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.809	100	0.978