Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MPG22_RS01910 Genome accession   NZ_CP094111
Coordinates   378737..380713 (+) Length   658 a.a.
NCBI ID   WP_245065526.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hpfe070     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 373737..385713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG22_RS01890 (MPG22_01890) ggt 374833..376536 (+) 1704 WP_245065520.1 gamma-glutamyltransferase -
  MPG22_RS01895 (MPG22_01895) - 376819..377589 (+) 771 WP_245065523.1 HP1117 family Sel1-like repeat protein -
  MPG22_RS01900 (MPG22_01900) - 377694..378077 (+) 384 WP_245065524.1 hypothetical protein -
  MPG22_RS01905 (MPG22_01905) - 378100..378696 (+) 597 Protein_372 DUF1542 domain-containing protein -
  MPG22_RS01910 (MPG22_01910) uvrB 378737..380713 (+) 1977 WP_245065526.1 excinuclease ABC subunit UvrB Machinery gene
  MPG22_RS01915 (MPG22_01915) - 380710..381543 (-) 834 WP_245065528.1 outer membrane protein -
  MPG22_RS01920 (MPG22_01920) purB 381606..382928 (-) 1323 WP_245065530.1 adenylosuccinate lyase -
  MPG22_RS01925 (MPG22_01925) - 383037..383981 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  MPG22_RS01930 (MPG22_01930) - 383994..385217 (-) 1224 WP_245065532.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  MPG22_RS01935 (MPG22_01935) - 385228..385620 (-) 393 WP_108378517.1 4Fe-4S dicluster domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75946.52 Da        Isoelectric Point: 6.9240

>NTDB_id=575156 MPG22_RS01910 WP_245065526.1 378737..380713(+) (uvrB) [Helicobacter pylori strain Hpfe070]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANVIAQINKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKDQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
LSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRALEEELKLRDDEIRIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=575156 MPG22_RS01910 WP_245065526.1 378737..380713(+) (uvrB) [Helicobacter pylori strain Hpfe070]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGAGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATGTCATCGCTC
AAATCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCACAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGTGCTTATAAGAGCTTTTTACTCAAACTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGTTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAACGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGATCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGTGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCCAATGAAACA
CCTTTTTGTTTGTTTGACTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGTGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCTGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTGTTTGATGAAATCAAGTTGGTGGTGGCTAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCATATTATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATTAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CTAAGCATGCAAAAAGCTTTTGAAATTACAAGCTACAGGCGTGCTAAGCAAGAAGAGTTCAATAAGCTTCATCATATCAC
TCCCAAAACCGTTACCCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGTGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGATGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)

Type III restriction enzyme, res subunit (ResIII)

(15-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498