Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NZ_AIDX01000001
Coordinates   1072595..1072690 (+) Length   32 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus canis FSL Z3-227     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 1067595..1077690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCAZ3_RS05035 (SCAZ3_00450) purE 1068099..1068590 (+) 492 WP_003046002.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  SCAZ3_RS05040 (SCAZ3_00455) purK 1068577..1069647 (+) 1071 WP_003046003.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SCAZ3_RS05045 (SCAZ3_00460) purB 1070165..1071457 (+) 1293 WP_003046005.1 adenylosuccinate lyase -
  SCAZ3_RS05050 (SCAZ3_00465) comR 1071594..1072505 (+) 912 WP_003046007.1 helix-turn-helix domain-containing protein Regulator
  SCAZ3_RS12085 (SCAZ3_00470) comS 1072595..1072690 (+) 96 WP_201281440.1 quorum-sensing system DWW-type pheromone Regulator
  SCAZ3_RS05055 (SCAZ3_00475) ruvB 1072726..1073724 (+) 999 WP_003046011.1 Holliday junction branch migration DNA helicase RuvB -
  SCAZ3_RS05060 (SCAZ3_00480) - 1073865..1074308 (+) 444 WP_003046014.1 low molecular weight protein-tyrosine-phosphatase -
  SCAZ3_RS05065 (SCAZ3_00485) - 1074325..1074726 (+) 402 WP_003046016.1 MORN repeat-containing protein -
  SCAZ3_RS05070 (SCAZ3_00490) - 1074723..1076498 (+) 1776 WP_003046018.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3831.68 Da        Isoelectric Point: 10.7919

>NTDB_id=575 1072595..1072690(+) (comS) [Streptococcus canis FSL Z3-227]
MFKKFKPFLLIAAVIAFKVARVMNEFDWWNLG

Nucleotide


Download         Length: 96 bp        

>NTDB_id=575 1072595..1072690(+) (comS) [Streptococcus canis FSL Z3-227]
ATGTTTAAAAAATTCAAACCATTTTTGTTAATAGCTGCGGTAATTGCTTTTAAAGTAGCTCGTGTGATGAATGAATTTGA
TTGGTGGAATCTAGGT

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

FDWWNLG


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

84.375

100

0.844

  comS Streptococcus pyogenes MGAS8232

41.935

96.875

0.406


Multiple sequence alignment