Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   KM776_RS15980 Genome accession   NZ_CP076290
Coordinates   3231685..3232329 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain Q12     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3226685..3237329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KM776_RS15945 (KM776_15945) - 3227870..3228301 (+) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -
  KM776_RS15950 (KM776_15950) - 3228301..3228642 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  KM776_RS15955 (KM776_15955) - 3228635..3230116 (+) 1482 WP_014305717.1 Na+/H+ antiporter subunit D -
  KM776_RS15960 (KM776_15960) - 3230122..3230598 (+) 477 WP_069013187.1 Na+/H+ antiporter subunit E -
  KM776_RS15965 (KM776_15965) - 3230598..3230882 (+) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  KM776_RS15970 (KM776_15970) mnhG 3230866..3231240 (+) 375 WP_046560012.1 monovalent cation/H(+) antiporter subunit G -
  KM776_RS15975 (KM776_15975) - 3231280..3231663 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  KM776_RS15980 (KM776_15980) comA 3231685..3232329 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  KM776_RS15985 (KM776_15985) comP 3232410..3234701 (-) 2292 WP_014305719.1 histidine kinase Regulator
  KM776_RS15990 (KM776_15990) comX 3234713..3234877 (-) 165 WP_007613432.1 competence pheromone ComX -
  KM776_RS15995 (KM776_15995) - 3234877..3235755 (-) 879 WP_024085740.1 polyprenyl synthetase family protein -
  KM776_RS16000 (KM776_16000) degQ 3235940..3236080 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  KM776_RS16005 (KM776_16005) - 3236546..3236887 (+) 342 WP_014305721.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=574488 KM776_RS15980 WP_003152052.1 3231685..3232329(-) (comA) [Bacillus velezensis strain Q12]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=574488 KM776_RS15980 WP_003152052.1 3231685..3232329(-) (comA) [Bacillus velezensis strain Q12]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864