Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   KM776_RS12885 Genome accession   NZ_CP076290
Coordinates   2637083..2637883 (-) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus velezensis strain Q12     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 2632083..2642883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KM776_RS12855 (KM776_12855) - 2632630..2633262 (+) 633 WP_014305389.1 helix-turn-helix domain-containing protein -
  KM776_RS12860 (KM776_12860) - 2633553..2633690 (+) 138 WP_014470646.1 hypothetical protein -
  KM776_RS12865 (KM776_12865) - 2633784..2634902 (+) 1119 WP_024085589.1 NADH-dependent flavin oxidoreductase -
  KM776_RS12870 (KM776_12870) - 2635028..2635240 (+) 213 WP_024085590.1 spore germination protein -
  KM776_RS12875 (KM776_12875) - 2635366..2635578 (+) 213 WP_014305392.1 spore germination protein -
  KM776_RS12880 (KM776_12880) alr 2635754..2636935 (+) 1182 WP_014305393.1 alanine racemase -
  KM776_RS12885 (KM776_12885) spo0A 2637083..2637883 (-) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  KM776_RS12890 (KM776_12890) spoIVB 2638164..2639444 (-) 1281 WP_014305394.1 SpoIVB peptidase -
  KM776_RS12895 (KM776_12895) recN 2639608..2641338 (-) 1731 WP_003153174.1 DNA repair protein RecN Machinery gene
  KM776_RS12900 (KM776_12900) argR 2641370..2641819 (-) 450 WP_003153173.1 transcriptional regulator ArgR -
  KM776_RS12905 (KM776_12905) - 2641916..2642761 (-) 846 WP_003153172.1 TlyA family RNA methyltransferase -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=574467 KM776_RS12885 WP_003153177.1 2637083..2637883(-) (spo0A) [Bacillus velezensis strain Q12]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=574467 KM776_RS12885 WP_003153177.1 2637083..2637883(-) (spo0A) [Bacillus velezensis strain Q12]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCCGATGTGCTCG
TGTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGTGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCATCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCCC
CGTCTGCGCAAAGCAGCATTATCCGCAGCCAGCCGGAGCCGAAGCGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACCGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATTTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAACCAACCAACTCGGAATTCATCGCGATGGTTGCTGACAAGCTGAGATTGGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97