Detailed information NTG0574119

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPG31_RS05350
• Genome accession: NZ_CP094074
• Coordinates: 1112295..1114877 (+)
• Length: 860 a.a.
• NCBI ID: WP_245015023.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe103
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1107295..1119877

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPG31_RS05310 (MPG31_05310)	-	1107586..1108872 (+)	1287	WP_245015018.1	MFS transporter	-
MPG31_RS05315 (MPG31_05315)	-	1108921..1109730 (+)	810	WP_001179215.1	flagellar hook-basal body protein	-
MPG31_RS05320 (MPG31_05320)	-	1109705..1109990 (-)	286	Protein_1037	hypothetical protein	-
MPG31_RS05325 (MPG31_05325)	-	1110121..1110909 (+)	789	WP_245015019.1	integrase	-
MPG31_RS05330 (MPG31_05330)	-	1111013..1111492 (+)	480	WP_245015020.1	hypothetical protein	-
MPG31_RS05335 (MPG31_05335)	comB2	1111489..1111773 (+)	285	WP_245015021.1	TrbC/VirB2 family protein	Machinery gene
MPG31_RS05340 (MPG31_05340)	comB3	1111785..1112048 (+)	264	WP_245015022.1	competence protein ComB	Machinery gene
MPG31_RS05345 (MPG31_05345)	-	1112059..1112295 (+)	237	WP_053574506.1	hypothetical protein	-
MPG31_RS05350 (MPG31_05350)	comB4	1112295..1114877 (+)	2583	WP_245015023.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPG31_RS05355 (MPG31_05355)	-	1114874..1115008 (+)	135	WP_000738749.1	hypothetical protein	-
MPG31_RS05360 (MPG31_05360)	-	1115001..1116170 (+)	1170	WP_245015024.1	VirB8/TrbF family protein	-
MPG31_RS05365 (MPG31_05365)	-	1116192..1117838 (+)	1647	WP_245015713.1	TrbG/VirB9 family P-type conjugative transfer protein	-
MPG31_RS05370 (MPG31_05370)	comB10	1117835..1119037 (+)	1203	WP_212866253.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 99076.16 Da
• Isoelectric Point: 8.6823

>NTDB_id=574119 MPG31_RS05350 WP_245015023.1 1112295..1114877(+) (comB4) [Helicobacter pylori strain Hpfe103]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TINKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVKETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGAIGAGKTTLISYLMMSALKYPNIDILAFDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSTSNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEYYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMINKEINKIITQARKANG
VIVLALQDINQLSEVKNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=574119 MPG31_RS05350 WP_245015023.1 1112295..1114877(+) (comB4) [Helicobacter pylori strain Hpfe103]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGACTTAGAGGGCTATTTTGATACTAGACAAAATGTTCTCAAC
ACCATTAATAAAGACATTCAATTAAGAATTGTGGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAT
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGTATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCTTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTCAAAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCCAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAATAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTTTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGCACAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAATGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAATACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCTTTGAAAATCAATCGTGGGTTTTTATGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATAAATAAAGAAATCAATAAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTCATTGTTCTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAAAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.206	97.791	0.462