Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KM400_RS06045 Genome accession   NZ_CP076187
Coordinates   1152254..1152937 (+) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus anthracis str. BF1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1147254..1157937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KM400_RS06025 (KM400_06020) - 1148360..1150006 (+) 1647 WP_000727259.1 peptide ABC transporter substrate-binding protein -
  KM400_RS06030 (KM400_06025) - 1150033..1150236 (-) 204 WP_000559980.1 hypothetical protein -
  KM400_RS06035 (KM400_06030) spx 1150808..1151203 (+) 396 WP_000258267.1 transcriptional regulator Spx -
  KM400_RS06040 (KM400_06035) - 1151253..1151927 (-) 675 WP_000362609.1 TerC family protein -
  KM400_RS06045 (KM400_06040) mecA 1152254..1152937 (+) 684 WP_000350710.1 adaptor protein MecA Regulator
  KM400_RS06050 (KM400_06045) - 1153010..1154554 (+) 1545 WP_000799204.1 cardiolipin synthase -
  KM400_RS06055 (KM400_06050) - 1154636..1155880 (+) 1245 WP_000612267.1 competence protein CoiA family protein -
  KM400_RS06060 (KM400_06055) pepF 1155931..1157757 (+) 1827 WP_000003398.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=573188 KM400_RS06045 WP_000350710.1 1152254..1152937(+) (mecA) [Bacillus anthracis str. BF1]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=573188 KM400_RS06045 WP_000350710.1 1152254..1152937(+) (mecA) [Bacillus anthracis str. BF1]
TTGGATATTGAAAGAATTAATGATCATACGATGAAGTTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGAACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564