Detailed information NTG0057279

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAI5S5_RS13465
• Genome accession: NC_020566
• Coordinates: 2657674..2658561 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2652674..2663561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI5S5_RS13430	-	2652693..2652785 (+)	93	WP_010956583.1	hypothetical protein	-
SAI5S5_RS13435 (SAI5S5_1019530)	-	2652893..2653390 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAI5S5_RS13440	-	2653400..2653660 (-)	261	WP_001791974.1	hypothetical protein	-
SAI5S5_RS13445	-	2654042..2654155 (-)	114	Protein_2548	hypothetical protein	-
SAI5S5_RS13455 (SAI5S5_1019540)	-	2654814..2656814 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAI5S5_RS13460 (SAI5S5_1019550)	-	2656811..2657566 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAI5S5_RS13465 (SAI5S5_1019560)	braS	2657674..2658561 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAI5S5_RS13470 (SAI5S5_1019570)	braR	2658572..2659237 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAI5S5_RS13475	-	2659263..2659463 (-)	201	WP_000604730.1	hypothetical protein	-
SAI5S5_RS13485 (SAI5S5_1019580)	-	2659661..2661085 (+)	1425	WP_015445964.1	alkaline phosphatase	-
SAI5S5_RS15230	-	2661145..2661246 (-)	102	WP_000731976.1	SE2200 family small protein	-
SAI5S5_RS13490 (SAI5S5_1019590)	-	2661368..2661823 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAI5S5_RS13495 (SAI5S5_1019600)	-	2662068..2662829 (-)	762	WP_015445965.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=57279 SAI5S5_RS13465 WP_000143425.1 2657674..2658561(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=57279 SAI5S5_RS13465 WP_000143425.1 2657674..2658561(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1