Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAI5S5_RS10195 Genome accession   NC_020566
Coordinates   2031522..2032238 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus ST228     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2026522..2037238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAI5S5_RS10165 (SAI5S5_1014870) - 2026739..2027365 (+) 627 WP_000522381.1 nitroreductase family protein -
  SAI5S5_RS10170 (SAI5S5_1014880) - 2027726..2028511 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  SAI5S5_RS15210 hld 2029111..2029191 (-) 81 WP_000046022.1 delta-hemolysin -
  SAI5S5_RS10180 (SAI5S5_1014890) - 2029481..2030044 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  SAI5S5_RS10185 agrD 2030047..2030190 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  SAI5S5_RS10190 (SAI5S5_1014900) agrC 2030220..2031503 (+) 1284 WP_015445896.1 quorum-sensing sensor histidine kinase AgrC -
  SAI5S5_RS10195 (SAI5S5_1014910) agrA 2031522..2032238 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SAI5S5_RS10200 - 2032310..2032419 (+) 110 Protein_1930 hypothetical protein -
  SAI5S5_RS10205 (SAI5S5_1014920) - 2032607..2033566 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  SAI5S5_RS10210 (SAI5S5_1014930) - 2033563..2035047 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  SAI5S5_RS10215 (SAI5S5_1014940) - 2035196..2036146 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=57275 SAI5S5_RS10195 WP_000688492.1 2031522..2032238(+) (agrA) [Staphylococcus aureus subsp. aureus ST228]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=57275 SAI5S5_RS10195 WP_000688492.1 2031522..2032238(+) (agrA) [Staphylococcus aureus subsp. aureus ST228]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment