Detailed information NTG0057236

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAI2T2_RS13465
• Genome accession: NC_020564
• Coordinates: 2657729..2658616 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2652729..2663616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI2T2_RS15230	-	2652748..2652840 (+)	93	WP_010956583.1	hypothetical protein	-
SAI2T2_RS13435 (SAI2T2_1019600)	-	2652948..2653445 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAI2T2_RS15235	-	2653455..2653715 (-)	261	WP_001791974.1	hypothetical protein	-
SAI2T2_RS15240	-	2654097..2654210 (-)	114	Protein_2554	hypothetical protein	-
SAI2T2_RS13455 (SAI2T2_1019610)	-	2654869..2656869 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAI2T2_RS13460 (SAI2T2_1019620)	-	2656866..2657621 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAI2T2_RS13465 (SAI2T2_1019630)	braS	2657729..2658616 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAI2T2_RS13470 (SAI2T2_1019640)	braR	2658627..2659292 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAI2T2_RS13475	-	2659318..2659518 (-)	201	WP_000604730.1	hypothetical protein	-
SAI2T2_RS13485 (SAI2T2_1019650)	-	2659716..2661140 (+)	1425	WP_015445964.1	alkaline phosphatase	-
SAI2T2_RS16100	-	2661210..2661320 (+)	111	Protein_2561	hypothetical protein	-
SAI2T2_RS13490 (SAI2T2_1019660)	-	2661423..2661878 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAI2T2_RS13495 (SAI2T2_1019670)	-	2662123..2662884 (-)	762	WP_015445965.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=57236 SAI2T2_RS13465 WP_000143425.1 2657729..2658616(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=57236 SAI2T2_RS13465 WP_000143425.1 2657729..2658616(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1