Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KM132_RS05830 Genome accession   NZ_CP076119
Coordinates   1147818..1148474 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain NZ4     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1142818..1153474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KM132_RS05805 (KM132_05805) oppF 1143349..1144266 (+) 918 WP_154817835.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KM132_RS05810 (KM132_05810) - 1144372..1145559 (+) 1188 WP_154817836.1 putative glycoside hydrolase -
  KM132_RS05815 (KM132_05815) - 1145677..1146255 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  KM132_RS05820 (KM132_05820) spx 1146434..1146829 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  KM132_RS05825 (KM132_05825) - 1146886..1147542 (-) 657 WP_014417421.1 TerC family protein -
  KM132_RS05830 (KM132_05830) mecA 1147818..1148474 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  KM132_RS05835 (KM132_05835) - 1148626..1149786 (+) 1161 WP_154817837.1 competence protein CoiA family protein -
  KM132_RS05840 (KM132_05840) pepF 1150014..1151843 (+) 1830 WP_154817838.1 oligoendopeptidase F Regulator
  KM132_RS05845 (KM132_05845) - 1151881..1152048 (-) 168 WP_003155026.1 hypothetical protein -
  KM132_RS05850 (KM132_05850) spxH 1152335..1153237 (-) 903 WP_154817839.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=572096 KM132_RS05830 WP_003155032.1 1147818..1148474(+) (mecA) [Bacillus velezensis strain NZ4]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=572096 KM132_RS05830 WP_003155032.1 1147818..1148474(+) (mecA) [Bacillus velezensis strain NZ4]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895