Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KH238_RS04340 Genome accession   NZ_CP076045
Coordinates   846420..847076 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain VCN56     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 841420..852076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KH238_RS04310 (KH238_04310) oppF 841949..842866 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KH238_RS04315 (KH238_04315) - 842973..844160 (+) 1188 WP_032866147.1 putative glycoside hydrolase -
  KH238_RS04320 (KH238_04320) - 844278..844856 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  KH238_RS04325 (KH238_04325) spx 845035..845430 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  KH238_RS04330 (KH238_04330) - 845488..846144 (-) 657 WP_032866146.1 TerC family protein -
  KH238_RS04335 (KH238_04335) - 846327..846437 (+) 111 Protein_842 adaptor protein MecA -
  KH238_RS04340 (KH238_04340) mecA 846420..847076 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  KH238_RS04345 (KH238_04345) - 847228..848388 (+) 1161 WP_032866145.1 competence protein CoiA family protein -
  KH238_RS04350 (KH238_04350) pepF 848616..850445 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  KH238_RS04355 (KH238_04355) - 850483..850650 (-) 168 WP_003155026.1 hypothetical protein -
  KH238_RS04360 (KH238_04360) spxH 850936..851838 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=571596 KH238_RS04340 WP_003155032.1 846420..847076(+) (mecA) [Bacillus velezensis strain VCN56]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=571596 KH238_RS04340 WP_003155032.1 846420..847076(+) (mecA) [Bacillus velezensis strain VCN56]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895