Detailed information NTG0571558

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KI244_RS07265
• Genome accession: NZ_CP076029
• Coordinates: 1459219..1460262 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus sp. MZ9
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1454219..1465262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KI244_RS07235 (KI244_07235)	-	1454641..1455897 (-)	1257	WP_001793428.1	aminopeptidase	-
KI244_RS07240 (KI244_07240)	-	1455900..1456100 (-)	201	WP_000180460.1	DUF1128 family protein	-
KI244_RS07245 (KI244_07245)	-	1456247..1456711 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KI244_RS07250 (KI244_07250)	-	1456718..1456993 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KI244_RS07255 (KI244_07255)	-	1457271..1458488 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
KI244_RS07260 (KI244_07260)	vraR	1458600..1459229 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KI244_RS07265 (KI244_07265)	vraS	1459219..1460262 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KI244_RS07270 (KI244_07270)	liaF	1460259..1460960 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KI244_RS07275 (KI244_07275)	-	1460975..1461361 (-)	387	WP_001110179.1	hypothetical protein	-
KI244_RS07280 (KI244_07280)	map	1461578..1462336 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KI244_RS07285 (KI244_07285)	-	1462867..1463853 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
KI244_RS07290 (KI244_07290)	-	1464343..1464756 (-)	414	WP_001670387.1	hypothetical protein	-
KI244_RS07295 (KI244_07295)	-	1464785..1464895 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=571558 KI244_RS07265 WP_001017131.1 1459219..1460262(-) (vraS) [Staphylococcus sp. MZ9]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=571558 KI244_RS07265 WP_001017131.1 1459219..1460262(-) (vraS) [Staphylococcus sp. MZ9]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1