Detailed information NTG0571438

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KI230_RS09795
• Genome accession: NZ_CP076026
• Coordinates: 2004988..2006031 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus sp. MZ3
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1999988..2011031

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KI230_RS09765 (KI230_09765)	-	2000410..2001666 (-)	1257	WP_001793428.1	aminopeptidase	-
KI230_RS09770 (KI230_09770)	-	2001669..2001869 (-)	201	WP_000180460.1	DUF1128 family protein	-
KI230_RS09775 (KI230_09775)	-	2002016..2002480 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KI230_RS09780 (KI230_09780)	-	2002487..2002762 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KI230_RS09785 (KI230_09785)	-	2003040..2004257 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
KI230_RS09790 (KI230_09790)	vraR	2004369..2004998 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KI230_RS09795 (KI230_09795)	vraS	2004988..2006031 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KI230_RS09800 (KI230_09800)	liaF	2006028..2006729 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KI230_RS09805 (KI230_09805)	-	2006744..2007130 (-)	387	WP_001110179.1	hypothetical protein	-
KI230_RS09810 (KI230_09810)	map	2007347..2008105 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KI230_RS09815 (KI230_09815)	-	2008636..2009622 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
KI230_RS09820 (KI230_09820)	-	2010112..2010525 (-)	414	WP_001670387.1	hypothetical protein	-
KI230_RS09825 (KI230_09825)	-	2010554..2010664 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=571438 KI230_RS09795 WP_001017131.1 2004988..2006031(-) (vraS) [Staphylococcus sp. MZ3]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=571438 KI230_RS09795 WP_001017131.1 2004988..2006031(-) (vraS) [Staphylococcus sp. MZ3]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1