Detailed information NTG0571396

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KI229_RS09675
• Genome accession: NZ_CP076025
• Coordinates: 1978160..1979203 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus sp. MZ1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1973160..1984203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KI229_RS09645 (KI229_09645)	-	1973582..1974838 (-)	1257	WP_001793428.1	aminopeptidase	-
KI229_RS09650 (KI229_09650)	-	1974841..1975041 (-)	201	WP_000180460.1	DUF1128 family protein	-
KI229_RS09655 (KI229_09655)	-	1975188..1975652 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KI229_RS09660 (KI229_09660)	-	1975659..1975934 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KI229_RS09665 (KI229_09665)	-	1976212..1977429 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
KI229_RS09670 (KI229_09670)	vraR	1977541..1978170 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KI229_RS09675 (KI229_09675)	vraS	1978160..1979203 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KI229_RS09680 (KI229_09680)	liaF	1979200..1979901 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KI229_RS09685 (KI229_09685)	-	1979916..1980302 (-)	387	WP_001110179.1	hypothetical protein	-
KI229_RS09690 (KI229_09690)	map	1980519..1981277 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KI229_RS09695 (KI229_09695)	-	1981808..1982794 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
KI229_RS09700 (KI229_09700)	-	1983284..1983697 (-)	414	WP_001670387.1	hypothetical protein	-
KI229_RS09705 (KI229_09705)	-	1983726..1983836 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=571396 KI229_RS09675 WP_001017131.1 1978160..1979203(-) (vraS) [Staphylococcus sp. MZ1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=571396 KI229_RS09675 WP_001017131.1 1978160..1979203(-) (vraS) [Staphylococcus sp. MZ1]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1