Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   M1GAS476_RS08690 Genome accession   NC_020540
Coordinates   1746816..1747529 (+) Length   237 a.a.
NCBI ID   WP_002992823.1    Uniprot ID   -
Organism   Streptococcus pyogenes M1 476     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1741816..1752529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M1GAS476_RS08680 (M1GAS476_1832) treC 1742886..1744514 (-) 1629 WP_010922745.1 alpha,alpha-phosphotrehalase -
  M1GAS476_RS08685 (M1GAS476_183) treP 1744581..1746605 (-) 2025 WP_010922746.1 PTS system trehalose-specific EIIBC component -
  M1GAS476_RS08690 (M1GAS476_1834) treR 1746816..1747529 (+) 714 WP_002992823.1 trehalose operon repressor Regulator
  M1GAS476_RS08695 - 1747808..1748146 (-) 339 Protein_1681 winged helix-turn-helix transcriptional regulator -
  M1GAS476_RS08700 (M1GAS476_1836) - 1748333..1749190 (+) 858 WP_010922747.1 VOC family protein -
  M1GAS476_RS08705 (M1GAS476_1837) yaaA 1749232..1749963 (+) 732 WP_010922748.1 peroxide stress protein YaaA -
  M1GAS476_RS08710 (M1GAS476_1838) nrdG 1750137..1750751 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  M1GAS476_RS08715 (M1GAS476_183) - 1750751..1751260 (-) 510 WP_011285759.1 GNAT family N-acetyltransferase -
  M1GAS476_RS08720 (M1GAS476_184) - 1751269..1752204 (-) 936 WP_010922750.1 Gfo/Idh/MocA family protein -
  M1GAS476_RS09895 - 1752233..1752379 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27620.79 Da        Isoelectric Point: 9.6307

>NTDB_id=57116 M1GAS476_RS08690 WP_002992823.1 1746816..1747529(+) (treR) [Streptococcus pyogenes M1 476]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=57116 M1GAS476_RS08690 WP_002992823.1 1746816..1747529(+) (treR) [Streptococcus pyogenes M1 476]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment