Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   M1GAS476_RS07325 Genome accession   NC_020540
Coordinates   1447460..1448185 (-) Length   241 a.a.
NCBI ID   WP_002983379.1    Uniprot ID   A0A4U7HHL6
Organism   Streptococcus pyogenes M1 476     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1442460..1453185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M1GAS476_RS07290 (M1GAS476_1543) - 1442594..1442977 (+) 384 WP_002988673.1 ImmA/IrrE family metallo-endopeptidase -
  M1GAS476_RS07295 (M1GAS476_1544) - 1442988..1443539 (+) 552 WP_002988670.1 hypothetical protein -
  M1GAS476_RS07300 (M1GAS476_1545) - 1443656..1444735 (+) 1080 WP_002988667.1 site-specific integrase -
  M1GAS476_RS07310 (M1GAS476_1547) trmB 1444933..1445568 (-) 636 WP_002983387.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  M1GAS476_RS07315 (M1GAS476_1548) ccrZ 1445568..1446359 (-) 792 WP_002983385.1 cell cycle regulator CcrZ -
  M1GAS476_RS07320 (M1GAS476_1549) - 1446423..1447457 (-) 1035 WP_010922583.1 ABC transporter permease -
  M1GAS476_RS07325 (M1GAS476_1550) pptA 1447460..1448185 (-) 726 WP_002983379.1 ABC transporter ATP-binding protein Regulator
  M1GAS476_RS07330 (M1GAS476_1551) - 1448257..1448676 (+) 420 WP_002983376.1 HIT family protein -
  M1GAS476_RS07335 (M1GAS476_155) - 1448673..1449029 (+) 357 WP_002988657.1 hypothetical protein -
  M1GAS476_RS07340 (M1GAS476_1553) brpA 1449140..1450414 (-) 1275 WP_010922584.1 biofilm formation/cell division transcriptional regulator BrpA -
  M1GAS476_RS07345 (M1GAS476_1554) - 1450423..1450947 (-) 525 WP_009880752.1 GNAT family N-acetyltransferase -
  M1GAS476_RS07350 tsaE 1450922..1451383 (-) 462 WP_009880751.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  M1GAS476_RS07355 (M1GAS476_1556) - 1451537..1452997 (-) 1461 WP_011285677.1 NCS2 family permease -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 26678.75 Da        Isoelectric Point: 4.5624

>NTDB_id=57104 M1GAS476_RS07325 WP_002983379.1 1447460..1448185(-) (pptA) [Streptococcus pyogenes M1 476]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide


Download         Length: 726 bp        

>NTDB_id=57104 M1GAS476_RS07325 WP_002983379.1 1447460..1448185(-) (pptA) [Streptococcus pyogenes M1 476]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7HHL6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.803

99.17

0.722
  pptA Streptococcus thermophilus LMD-9

71.967

99.17

0.714

Multiple sequence alignment