Detailed information NTG0057029

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ATE38_RS11245
• Genome accession: NZ_AP017377
• Coordinates: 2148555..2149262 (+)
• Length: 235 a.a.
• NCBI ID: WP_000094093.1
• Uniprot ID: A0A1D4DWM6
• Organism: Staphylococcus aureus strain OC8
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2143555..2154262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATE38_RS11190	-	2144309..2144572 (-)	264	WP_001205732.1	hypothetical protein	-
ATE38_RS11195	-	2144581..2144841 (-)	261	WP_000291489.1	DUF1108 family protein	-
ATE38_RS11200	-	2144934..2145095 (-)	162	WP_000066020.1	DUF1270 domain-containing protein	-
ATE38_RS11205	-	2145092..2145412 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
ATE38_RS11210	-	2145471..2146103 (+)	633	WP_000275058.1	hypothetical protein	-
ATE38_RS11215	-	2146118..2146258 (-)	141	WP_000939496.1	hypothetical protein	-
ATE38_RS11220	-	2146289..2146483 (-)	195	WP_000388066.1	hypothetical protein	-
ATE38_RS11225	-	2146500..2147252 (-)	753	WP_001148618.1	phage antirepressor KilAC domain-containing protein	-
ATE38_RS11230	-	2147309..2147848 (+)	540	WP_000351243.1	hypothetical protein	-
ATE38_RS11235	-	2147872..2148132 (-)	261	WP_000435341.1	transcriptional regulator	-
ATE38_RS11240	-	2148145..2148384 (-)	240	WP_000548578.1	helix-turn-helix transcriptional regulator	-
ATE38_RS11245	irvR	2148555..2149262 (+)	708	WP_000094093.1	XRE family transcriptional regulator	Regulator
ATE38_RS15350	-	2149274..2149429 (+)	156	WP_001049399.1	hypothetical protein	-
ATE38_RS11250	-	2149416..2149601 (+)	186	WP_001089804.1	hypothetical protein	-
ATE38_RS11255	-	2149801..2149968 (+)	168	WP_000705238.1	hypothetical protein	-
ATE38_RS11260	-	2150108..2150647 (+)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
ATE38_RS11265	-	2150820..2151857 (+)	1038	WP_000857198.1	site-specific integrase	-
ATE38_RS11270	sph	2151908..2152753 (+)	846	Protein_2098	sphingomyelin phosphodiesterase	-
ATE38_RS11275	lukG	2152976..2153992 (-)	1017	WP_000595324.1	bi-component leukocidin LukGH subunit G	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26769.35 Da
• Isoelectric Point: 5.4082

>NTDB_id=57029 ATE38_RS11245 WP_000094093.1 2148555..2149262(+) (irvR) [Staphylococcus aureus strain OC8]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide

• Length: 708 bp

>NTDB_id=57029 ATE38_RS11245 WP_000094093.1 2148555..2149262(+) (irvR) [Staphylococcus aureus strain OC8]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (123-234)

• Helix-turn-helix (HTH_3) (8-61)

3D structure

• AlphaFold DB: A0A1D4DWM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	30.769	100	0.374