Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KJP35_RS05695 Genome accession   NZ_CP075563
Coordinates   1179356..1180072 (-) Length   238 a.a.
NCBI ID   WP_255777496.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Sta2021027     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174356..1185072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJP35_RS05675 (KJP35_05625) - 1175448..1176398 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  KJP35_RS05680 (KJP35_05630) - 1176547..1178031 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  KJP35_RS05685 (KJP35_05635) - 1178028..1178987 (+) 960 WP_001253310.1 carbohydrate kinase -
  KJP35_RS05690 (KJP35_05640) - 1179175..1179284 (-) 110 Protein_1115 hypothetical protein -
  KJP35_RS05695 (KJP35_05645) agrA 1179356..1180072 (-) 717 WP_255777496.1 quorum-sensing response regulator AgrA Regulator
  KJP35_RS05700 (KJP35_05650) agrC 1180091..1181383 (-) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  KJP35_RS05705 (KJP35_05655) agrD 1181408..1181548 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KJP35_RS05710 (KJP35_05660) agrB 1181545..1182114 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  KJP35_RS05715 (KJP35_05665) - 1182350..1182484 (+) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  KJP35_RS05720 (KJP35_05670) - 1183081..1183866 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  KJP35_RS05725 (KJP35_05675) - 1184227..1184853 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27964.93 Da        Isoelectric Point: 6.0927

>NTDB_id=569634 KJP35_RS05695 WP_255777496.1 1179356..1180072(-) (agrA) [Staphylococcus aureus strain Sta2021027]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDQ
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=569634 KJP35_RS05695 WP_255777496.1 1179356..1180072(-) (agrA) [Staphylococcus aureus strain Sta2021027]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCAA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992