Detailed information NTG0569621

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KI818_RS11250
• Genome accession: NZ_CP075562
• Coordinates: 2207607..2208494 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain Sta2021010
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2202607..2213494

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KI818_RS11220 (KI818_11180)	-	2202635..2202718 (+)	84	WP_031797553.1	hypothetical protein	-
KI818_RS11225 (KI818_11185)	-	2202826..2203323 (-)	498	WP_001065268.1	glutathione peroxidase	-
KI818_RS11230 (KI818_11190)	-	2203333..2203593 (-)	261	WP_001789307.1	hypothetical protein	-
KI818_RS11235 (KI818_11195)	-	2203975..2204088 (-)	114	WP_011447078.1	hypothetical protein	-
KI818_RS11240 (KI818_11200)	-	2204747..2206747 (-)	2001	WP_000776733.1	ABC transporter permease	-
KI818_RS11245 (KI818_11205)	-	2206744..2207499 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KI818_RS11250 (KI818_11210)	braS	2207607..2208494 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KI818_RS11255 (KI818_11215)	braR	2208505..2209170 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KI818_RS11260 (KI818_11220)	-	2209196..2209396 (-)	201	WP_000604727.1	hypothetical protein	-
KI818_RS11265 (KI818_11225)	-	2209594..2211018 (+)	1425	WP_000953744.1	alkaline phosphatase	-
KI818_RS14160	-	2211078..2211179 (-)	102	WP_000731972.1	SE2200 family small protein	-
KI818_RS11275 (KI818_11235)	-	2211301..2211756 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KI818_RS11280 (KI818_11240)	-	2212001..2212762 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=569621 KI818_RS11250 WP_000143419.1 2207607..2208494(-) (braS) [Staphylococcus aureus strain Sta2021010]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=569621 KI818_RS11250 WP_000143419.1 2207607..2208494(-) (braS) [Staphylococcus aureus strain Sta2021010]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997