Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ML603_RS07305 Genome accession   NZ_CP092887
Coordinates   1480278..1480919 (-) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1475278..1485919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS07285 (ML603_07285) - 1476653..1477291 (+) 639 WP_003062333.1 YigZ family protein -
  ML603_RS07290 (ML603_07290) cysK 1477395..1478330 (+) 936 WP_138126234.1 cysteine synthase A -
  ML603_RS07295 (ML603_07295) - 1478482..1478841 (-) 360 WP_111717284.1 S1 RNA-binding domain-containing protein -
  ML603_RS07300 (ML603_07300) - 1478841..1480241 (-) 1401 WP_138126238.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ML603_RS07305 (ML603_07305) vraR 1480278..1480919 (-) 642 WP_014612503.1 response regulator transcription factor Regulator
  ML603_RS07310 (ML603_07310) - 1480912..1481916 (-) 1005 WP_003061197.1 sensor histidine kinase -
  ML603_RS07315 (ML603_07315) liaF 1481913..1482605 (-) 693 WP_241066981.1 cell wall-active antibiotics response protein LiaF -
  ML603_RS07320 (ML603_07320) pknB 1482732..1484627 (-) 1896 WP_003052158.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ML603_RS07325 (ML603_07325) - 1484624..1485364 (-) 741 WP_003061786.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=568779 ML603_RS07305 WP_014612503.1 1480278..1480919(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=568779 ML603_RS07305 WP_014612503.1 1480278..1480919(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTACTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGTGTTGAGGCGACCTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACTTCTTATTTGGACAATGAGAAAATTTACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGGGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGACCAACACCCCGATTTGCATGAAGAGCTAACCGCGCGCGAGTATGATATTTTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTTAAAACGCATGTGTCTAATATTCT
TGCTAAGCTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376