Detailed information NTG0056833

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NJAUSS_RS08115
• Genome accession: NC_020526
• Coordinates: 1636633..1637682 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis SC070731
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1631633..1642682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NJAUSS_RS08095 (NJAUSS_1547)	nadE	1632039..1632863 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NJAUSS_RS08100 (NJAUSS_1548)	-	1634159..1634686 (-)	528	WP_012027591.1	VanZ family protein	-
NJAUSS_RS08105 (NJAUSS_1549)	rlmN	1634683..1635795 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NJAUSS_RS08110 (NJAUSS_1550)	-	1635804..1636445 (-)	642	WP_012027595.1	YutD family protein	-
NJAUSS_RS08115 (NJAUSS_1551)	sepM	1636633..1637682 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NJAUSS_RS08120 (NJAUSS_1552)	coaD	1637669..1638157 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
NJAUSS_RS08125 (NJAUSS_1553)	rsmD	1638147..1638686 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NJAUSS_RS08130 (NJAUSS_1554)	-	1638994..1639716 (-)	723	WP_012027598.1	lipoprotein	-
NJAUSS_RS08135 (NJAUSS_1555)	-	1639773..1640159 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NJAUSS_RS08140 (NJAUSS_1556)	-	1640159..1640377 (-)	219	WP_004194736.1	YqgQ family protein	-
NJAUSS_RS08145 (NJAUSS_1557)	-	1640685..1641287 (-)	603	WP_012027601.1	response regulator transcription factor	-
NJAUSS_RS08150 (NJAUSS_1558)	-	1641284..1642378 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=56833 NJAUSS_RS08115 WP_012775295.1 1636633..1637682(-) (sepM) [Streptococcus suis SC070731]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=56833 NJAUSS_RS08115 WP_012775295.1 1636633..1637682(-) (sepM) [Streptococcus suis SC070731]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605