Detailed information NTG0568173

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: MK616_RS00590
• Genome accession: NZ_CP092778
• Coordinates: 108025..109107 (+)
• Length: 360 a.a.
• NCBI ID: WP_003156401.1
• Uniprot ID: A0AAI8HS26
• Organism: Bacillus amyloliquefaciens strain WF2020
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 103025..114107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MK616_RS00575 (MK616_00575)	-	103028..104119 (+)	1092	WP_003156398.1	protein arginine kinase	-
MK616_RS00580 (MK616_00580)	clpC	104116..106548 (+)	2433	WP_007410388.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
MK616_RS00585 (MK616_00585)	radA/sms	106642..108021 (+)	1380	WP_014416742.1	DNA repair protein RadA	Machinery gene
MK616_RS00590 (MK616_00590)	disA	108025..109107 (+)	1083	WP_003156401.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
MK616_RS00595 (MK616_00595)	-	109221..110321 (+)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
MK616_RS00600 (MK616_00600)	ispD	110334..111032 (+)	699	WP_017419469.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
MK616_RS00605 (MK616_00605)	ispF	111025..111501 (+)	477	WP_022552481.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
MK616_RS00610 (MK616_00610)	gltX	111593..113044 (+)	1452	WP_240680121.1	glutamate--tRNA ligase	-
MK616_RS00615 (MK616_00615)	cysE	113355..114008 (+)	654	WP_007410393.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40671.21 Da
• Isoelectric Point: 5.5321

>NTDB_id=568173 MK616_RS00590 WP_003156401.1 108025..109107(+) (disA) [Bacillus amyloliquefaciens strain WF2020]
MEKEKKGAKQELDLSAILQFVAPGTPLRAGIENVLRANTGGLIVVGYNDKVKQVVDGGFHINTSFAPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPEATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQDSMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTITALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIRLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSILFKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGFLPS
ITEATVEELDDVEGIGEVRAQKIKKGLKRLQEKHYIDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=568173 MK616_RS00590 WP_003156401.1 108025..109107(+) (disA) [Bacillus amyloliquefaciens strain WF2020]
ATGGAAAAAGAGAAAAAAGGGGCGAAACAAGAGCTTGACCTGTCTGCAATTCTGCAGTTCGTTGCACCGGGCACCCCGCT
CAGAGCCGGGATAGAGAATGTACTTCGGGCAAATACAGGCGGCCTGATTGTTGTCGGATACAATGATAAGGTAAAGCAAG
TCGTCGATGGCGGTTTTCATATTAATACATCATTTGCGCCCGCTCACTTATACGAGCTGGCCAAAATGGACGGTGCCATT
ATTTTAAGTGATTCCGGCCAGAAAATTCTTTATGCGAATACGCAGCTTATGCCGGAGGCGACCATTTCTTCTTCAGAAAC
GGGAATGAGGCACCGTACGGCGGAACGGGTGGCGAAGCAGACCGGCTGTCTCGTCATTGCCATTTCTGAGCGCAGAAATG
TCATTACGTTATATCAGGACAGCATGAAGTACACACTAAAGGACATAGGATTTATTTTAACAAAGGCAAATCAGGCCATT
CAAACGCTTGAGAAGTATAAAACCATTTTAGACAAAACGATTACGGCTTTAAACGCATTAGAGTTTGAGGAGCTTGTGAC
ATTCAGTGACGTGCTGTCCGTCATGCATCGGTATGAAATGGTGCTCCGAATAAAAAATGAAATCAATATGTATATTAAAG
AACTCGGAACGGAAGGCCACTTAATCCGTCTGCAGGTGATTGAACTGATTACGGACATGGAAGAAGAGGCGGCACTTTTC
ATCAAAGACTATGTCAAAGAAAAAATCAAAGATCCGTTCGTGCTGTTAAAAGAGCTTCAGGATATGTCCAGCTATGATCT
GCTTGATGATTCCATTCTGTTTAAGCTGCTTGGATATCCGGCTTCTACGAATCTTGATGATTATGTGCTCCCGAGAGGAT
ACAGGCTGCTGAACAAAATTCCGCGTCTGCCGATGCCGATTGTTGAAAATGTGGTTGAGGCGTTCGGATTTTTGCCAAGC
ATAACGGAAGCCACTGTGGAAGAGCTTGATGATGTCGAGGGTATCGGAGAAGTGCGCGCCCAAAAAATCAAAAAAGGCTT
AAAACGCCTTCAGGAAAAACACTATATAGATAGACAGCTTTAA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: A0AAI8HS26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	94.444	100	0.944