Detailed information NTG0056770

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: LPE509_RS05945
• Genome accession: NC_020521
• Coordinates: 1335610..1338342 (-)
• Length: 910 a.a.
• NCBI ID: WP_010947629.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila LPE509
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1330610..1343342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPE509_RS05920 (LPE509_01272)	-	1331136..1332557 (-)	1422	WP_010947634.1	APC family permease	-
LPE509_RS05925 (LPE509_01274)	-	1332632..1332949 (-)	318	WP_010947633.1	BolA family transcriptional regulator	-
LPE509_RS05930 (LPE509_01275)	pilA2	1333252..1333662 (+)	411	WP_016356941.1	pilin	Machinery gene
LPE509_RS05935 (LPE509_01276)	pilA2	1333859..1334272 (+)	414	WP_015444381.1	pilin	Machinery gene
LPE509_RS05940 (LPE509_01277)	-	1334269..1335513 (-)	1245	WP_010947630.1	6-phosphofructokinase	-
LPE509_RS05945 (LPE509_01278)	letS	1335610..1338342 (-)	2733	WP_010947629.1	two-component system sensor histidine kinase LetS	Regulator
LPE509_RS05950 (LPE509_01279)	gltX	1338441..1339853 (+)	1413	WP_015444383.1	glutamate--tRNA ligase	-
LPE509_RS05955 (LPE509_01280)	-	1340100..1341362 (+)	1263	WP_010947627.1	serine hydrolase	-
LPE509_RS05960 (LPE509_01281)	-	1341403..1342398 (+)	996	WP_015444384.1	hypothetical protein	-
LPE509_RS05965 (LPE509_01282)	gstA	1342594..1343199 (+)	606	WP_015444385.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103050.55 Da
• Isoelectric Point: 7.6619

>NTDB_id=56770 LPE509_RS05945 WP_010947629.1 1335610..1338342(-) (letS) [Legionella pneumophila subsp. pneumophila LPE509]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKELSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSSDLSSIDMKKYGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIGLMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLERLARRT
ANADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=56770 LPE509_RS05945 WP_010947629.1 1335610..1338342(-) (letS) [Legionella pneumophila subsp. pneumophila LPE509]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGCAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCT
GAGGTAAAAGCTTTGGCATTTTATAATGCTGATGGTCGATTAATCGCTTATCGTGGTGGCAAGCACTCTATTCATAAACC
ATTCAATCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAATCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAATTCAAAGAGCTTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACCCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGCAATGAATTTGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCACCACATTGAAATCGCCAC
AGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATTGAGCTATCGCTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATTCGTACCCCAATGAATGGCGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACATAA
GAGGTTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATCGATTTAATCCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGCACTAAAATCGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCAGGATTAGGCTTGGTTATATGTAAAAAACTATGTGAAGAAATGCATGGGCGTATTAGTCT
AACCAGTGAAATCAACAAAGGTTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATAGGTAATGGC
TTGGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAATCAAGGATGTGAGCGACAAGCTGCTGAACTCATTGCCAAACACAAGCAAATTCCTT
TCGTGTTAATTTCCAAATGGCCTATTAATGATTTTGCGGCGCTTGGTGCTCGGGGTTTTCTTTACAAACCTATCAGCATC
CAAAAGCTTCAGGATCTGATTGAATCGATAGCCAATGAAAACCAAACTGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGCGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACCACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCATATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGTCAAAAATCCCTAATGAA
TAAACACTCTCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATATGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAGCAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATTGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTTATAGAAGA
ATTATATAAGAATCGTGAAGAGTTTATTGGGTTAATGCATCAAAAAAACGTAAAGGGCCTGGCTGATTTGGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGCGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAGGCTTGCAAGACGAACC
GCTAATGCTGATAATTTAACCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTACTCACAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-899)

• Response regulator receiver domain (Response_reg) (678-787)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.341	100	0.993