Detailed information NTG0567156

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: MKI52_RS08260
• Genome accession: NZ_CP092581
• Coordinates: 1726723..1727997 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain VRMSSA-WC111
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1721723..1732997

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI52_RS08240 (MKI52_001633)	-	1723047..1723142 (+)	96	WP_031761395.1	hypothetical protein	-
MKI52_RS08245 (MKI52_001634)	-	1723103..1724233 (-)	1131	WP_000721699.1	HAD family hydrolase	-
MKI52_RS08250 (MKI52_001635)	nagE	1724340..1725806 (-)	1467	WP_000276368.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
MKI52_RS08255 (MKI52_001636)	-	1725934..1726551 (-)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
MKI52_RS08260 (MKI52_001637)	htrA	1726723..1727997 (+)	1275	WP_001279338.1	trypsin-like peptidase domain-containing protein	Regulator
MKI52_RS08265 (MKI52_001638)	tyrS	1728091..1729353 (-)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
MKI52_RS08270 (MKI52_001639)	-	1729735..1730640 (+)	906	WP_000184370.1	transglycosylase domain-containing protein	-
MKI52_RS08275 (MKI52_001640)	-	1730620..1730712 (-)	93	WP_031761401.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=567156 MKI52_RS08260 WP_001279338.1 1726723..1727997(+) (htrA) [Staphylococcus aureus strain VRMSSA-WC111]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=567156 MKI52_RS08260 WP_001279338.1 1726723..1727997(+) (htrA) [Staphylococcus aureus strain VRMSSA-WC111]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37