Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPOK310_RS02655 Genome accession   NC_020509
Coordinates   540632..542416 (-) Length   594 a.a.
NCBI ID   WP_015428876.1    Uniprot ID   -
Organism   Helicobacter pylori OK310     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 535632..547416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPOK310_RS02625 (HPOK310_0517) - 536220..536468 (+) 249 WP_000790557.1 RNA-binding protein -
  HPOK310_RS02630 (HPOK310_0518) - 536673..537494 (-) 822 WP_015428873.1 glycosyltransferase family 25 protein -
  HPOK310_RS02635 (HPOK310_0519) trxB 537661..538596 (-) 936 WP_015428874.1 thioredoxin-disulfide reductase -
  HPOK310_RS02640 (HPOK310_0520) trxA 538602..538922 (-) 321 WP_000020197.1 thioredoxin -
  HPOK310_RS02645 (HPOK310_0521) - 539011..539355 (-) 345 WP_001211669.1 YraN family protein -
  HPOK310_RS02650 (HPOK310_0522) - 539356..540621 (-) 1266 WP_015428875.1 homoserine dehydrogenase -
  HPOK310_RS02655 (HPOK310_0523) uvrC 540632..542416 (-) 1785 WP_015428876.1 excinuclease ABC subunit UvrC Machinery gene
  HPOK310_RS02660 (HPOK310_0524) - 542417..542878 (-) 462 WP_000437184.1 hypothetical protein -
  HPOK310_RS02665 (HPOK310_0525) - 542870..543049 (+) 180 WP_000468796.1 hypothetical protein -
  HPOK310_RS02670 (HPOK310_0526) - 543061..543702 (-) 642 WP_015428877.1 ATP-binding cassette domain-containing protein -
  HPOK310_RS02675 (HPOK310_0527) - 543706..545262 (-) 1557 WP_015428878.1 ABC transporter permease/substrate-binding protein -
  HPOK310_RS02680 (HPOK310_0528) - 545362..545799 (-) 438 WP_015428879.1 hypothetical protein -
  HPOK310_RS02685 (HPOK310_0529) motB 545803..546570 (-) 768 WP_001085303.1 flagellar motor protein MotB -
  HPOK310_RS02690 (HPOK310_0530) motA 546573..547346 (-) 774 WP_000366176.1 flagellar motor stator protein MotA -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68748.05 Da        Isoelectric Point: 9.5939

>NTDB_id=56645 HPOK310_RS02655 WP_015428876.1 540632..542416(-) (uvrC) [Helicobacter pylori OK310]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVCNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQCSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDA
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGM
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=56645 HPOK310_RS02655 WP_015428876.1 540632..542416(-) (uvrC) [Helicobacter pylori OK310]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCTGTAATAATGAAATCACGCCCA
ATCATCGCACAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAAGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGTTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATGCTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGCA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATCAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAGCAAATCGCTCTTTTAAAAGAAAAGGGTATG
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAAGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965

Multiple sequence alignment