Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPOK113_RS04245 Genome accession   NC_020508
Coordinates   883618..885402 (+) Length   594 a.a.
NCBI ID   WP_015427934.1    Uniprot ID   -
Organism   Helicobacter pylori OK113     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 878618..890402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPOK113_RS04210 (HPOK113_0828) motA 878689..879462 (+) 774 WP_015427930.1 flagellar motor stator protein MotA -
  HPOK113_RS04215 (HPOK113_0829) motB 879465..880232 (+) 768 WP_001085303.1 flagellar motor protein MotB -
  HPOK113_RS04220 (HPOK113_0830) - 880236..880673 (+) 438 WP_015427931.1 hypothetical protein -
  HPOK113_RS04225 (HPOK113_0831) - 880774..882330 (+) 1557 WP_015427932.1 ABC transporter permease/substrate-binding protein -
  HPOK113_RS04230 (HPOK113_0832) - 882332..882973 (+) 642 WP_015427933.1 ABC transporter ATP-binding protein -
  HPOK113_RS04235 (HPOK113_0833) - 882985..883164 (-) 180 WP_000468796.1 hypothetical protein -
  HPOK113_RS04240 (HPOK113_0834) - 883156..883617 (+) 462 WP_000437191.1 hypothetical protein -
  HPOK113_RS04245 (HPOK113_0835) uvrC 883618..885402 (+) 1785 WP_015427934.1 excinuclease ABC subunit UvrC Machinery gene
  HPOK113_RS04250 (HPOK113_0836) - 885413..886678 (+) 1266 WP_015427935.1 homoserine dehydrogenase -
  HPOK113_RS04255 (HPOK113_0837) - 886679..887023 (+) 345 WP_015427936.1 YraN family protein -
  HPOK113_RS04260 (HPOK113_0838) trxA 887112..887432 (+) 321 WP_000020199.1 thioredoxin -
  HPOK113_RS04265 (HPOK113_0839) trxB 887438..888373 (+) 936 WP_015427937.1 thioredoxin-disulfide reductase -
  HPOK113_RS04270 (HPOK113_0840) - 888541..889362 (+) 822 WP_015427938.1 glycosyltransferase family 25 protein -
  HPOK113_RS04275 (HPOK113_0841) - 889568..889816 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68802.14 Da        Isoelectric Point: 9.7098

>NTDB_id=56626 HPOK113_RS04245 WP_015427934.1 883618..885402(+) (uvrC) [Helicobacter pylori OK113]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=56626 HPOK113_RS04245 WP_015427934.1 883618..885402(+) (uvrC) [Helicobacter pylori OK113]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAGTATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGCAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAGAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGAGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.643

100

0.976

Multiple sequence alignment