Detailed information
Bioinformatically predicted
Overview
| Name | sxy/tfoX | Type | Regulator |
| Locus tag | KIM45_RS09675 | Genome accession | NZ_CP074766 |
| Coordinates | 1981120..1981749 (+) | Length | 209 a.a. |
| NCBI ID | WP_000839153.1 | Uniprot ID | A0A9Q6Y251 |
| Organism | Escherichia coli strain 99_0849 | ||
| Function | positive regulator of competence gene (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1968617..2006944 | 1981120..1981749 | within | 0 |
Gene organization within MGE regions
Location: 1968617..2006944
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KIM45_RS09625 (KIM45_09485) | uup | 1969947..1971854 (+) | 1908 | WP_000053122.1 | ABC transporter ATP-binding protein | - |
| KIM45_RS09630 (KIM45_09490) | pqiA | 1971984..1973237 (+) | 1254 | WP_000333176.1 | membrane integrity-associated transporter subunit PqiA | - |
| KIM45_RS09635 (KIM45_09495) | pqiB | 1973242..1974882 (+) | 1641 | WP_000445533.1 | intermembrane transport protein PqiB | - |
| KIM45_RS09640 (KIM45_09500) | pqiC | 1974879..1975442 (+) | 564 | WP_133394983.1 | membrane integrity-associated transporter subunit PqiC | - |
| KIM45_RS09645 (KIM45_09505) | rmf | 1975698..1975865 (+) | 168 | WP_000828648.1 | ribosome modulation factor | - |
| KIM45_RS09650 (KIM45_09510) | fabA | 1975935..1976453 (-) | 519 | WP_000227927.1 | bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase | - |
| KIM45_RS09655 (KIM45_09515) | ycbZ | 1976522..1978282 (-) | 1761 | WP_000156528.1 | AAA family ATPase | - |
| KIM45_RS09660 (KIM45_09520) | matP | 1978468..1978920 (+) | 453 | WP_000877161.1 | macrodomain Ter protein MatP | - |
| KIM45_RS09665 (KIM45_09525) | ompA | 1978995..1980035 (-) | 1041 | WP_000750416.1 | porin OmpA | - |
| KIM45_RS09670 (KIM45_09530) | sulA | 1980392..1980901 (-) | 510 | WP_000288710.1 | SOS-induced cell division inhibitor SulA | - |
| KIM45_RS09675 (KIM45_09535) | sxy/tfoX | 1981120..1981749 (+) | 630 | WP_000839153.1 | CRP-S regulon transcriptional coactivator Sxy | Regulator |
| KIM45_RS09680 (KIM45_09540) | yccS | 1981712..1983874 (-) | 2163 | WP_000875023.1 | YccS family putative transporter | - |
| KIM45_RS09685 (KIM45_09545) | yccF | 1983884..1984330 (-) | 447 | WP_001261235.1 | YccF domain-containing protein | - |
| KIM45_RS09690 (KIM45_09550) | helD | 1984453..1986507 (+) | 2055 | WP_001297106.1 | DNA helicase IV | - |
| KIM45_RS09695 (KIM45_09555) | mgsA | 1986539..1986997 (-) | 459 | WP_000424181.1 | methylglyoxal synthase | - |
| KIM45_RS09700 (KIM45_09560) | csgI | 1987093..1987755 (-) | 663 | WP_000847791.1 | DUF2057 family protein | - |
| KIM45_RS09705 (KIM45_09565) | yccU | 1987928..1988341 (+) | 414 | WP_000665217.1 | CoA-binding protein | - |
| KIM45_RS09710 (KIM45_09570) | hspQ | 1988386..1988703 (-) | 318 | WP_001295356.1 | heat shock protein HspQ | - |
| KIM45_RS09715 (KIM45_09575) | rlmI | 1988761..1989951 (-) | 1191 | WP_000116304.1 | 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI | - |
| KIM45_RS09720 (KIM45_09580) | yccX | 1990046..1990324 (+) | 279 | WP_000048244.1 | acylphosphatase | - |
| KIM45_RS09725 (KIM45_09585) | tusE | 1990321..1990650 (-) | 330 | WP_000904442.1 | sulfurtransferase TusE | - |
| KIM45_RS09730 (KIM45_09590) | yccA | 1990741..1991400 (-) | 660 | WP_000375138.1 | FtsH protease modulator YccA | - |
| KIM45_RS09735 (KIM45_09595) | - | 1991808..1992827 (-) | 1020 | WP_001299351.1 | tyrosine-type recombinase/integrase | - |
| KIM45_RS09740 (KIM45_09600) | - | 1992805..1993047 (-) | 243 | WP_000273151.1 | DUF4224 domain-containing protein | - |
| KIM45_RS09745 (KIM45_09605) | - | 1993115..1995565 (-) | 2451 | WP_133394984.1 | exonuclease | - |
| KIM45_RS09750 (KIM45_09610) | - | 1995660..1995848 (-) | 189 | WP_000199475.1 | DUF1482 family protein | - |
| KIM45_RS09755 (KIM45_09615) | dicB | 1995845..1996033 (-) | 189 | WP_000449175.1 | cell division inhibition protein DicB | - |
| KIM45_RS09760 (KIM45_09620) | ydfC | 1996602..1996820 (-) | 219 | WP_001171921.1 | protein YdfC | - |
| KIM45_RS09765 | - | 1996913..1997113 (+) | 201 | WP_024182289.1 | ECs_2282 family putative zinc-binding protein | - |
| KIM45_RS09770 (KIM45_09630) | - | 1997527..1997829 (+) | 303 | WP_000692026.1 | type II toxin-antitoxin system HigB family toxin | - |
| KIM45_RS09775 (KIM45_09635) | - | 1997832..1998191 (+) | 360 | WP_001022415.1 | helix-turn-helix domain-containing protein | - |
| KIM45_RS09780 (KIM45_09640) | - | 1998238..1998630 (-) | 393 | WP_000578360.1 | helix-turn-helix domain-containing protein | - |
| KIM45_RS09785 (KIM45_09645) | - | 1998757..1999017 (+) | 261 | WP_001172789.1 | transcriptional regulator | - |
| KIM45_RS09790 (KIM45_09650) | - | 1999014..1999451 (+) | 438 | WP_000693932.1 | toxin YdaT family protein | - |
| KIM45_RS09795 (KIM45_09655) | - | 1999538..2000548 (+) | 1011 | WP_000729535.1 | DUF1376 domain-containing protein | - |
| KIM45_RS09800 (KIM45_09660) | - | 2000541..2001002 (+) | 462 | WP_000139444.1 | replication protein P | - |
| KIM45_RS09805 (KIM45_09665) | - | 2001036..2001761 (+) | 726 | WP_000450641.1 | DUF1627 domain-containing protein | - |
| KIM45_RS09810 (KIM45_09670) | - | 2001777..2002169 (+) | 393 | WP_001040234.1 | DUF977 family protein | - |
| KIM45_RS09815 (KIM45_09675) | - | 2002166..2002462 (+) | 297 | WP_001266133.1 | DUF4406 domain-containing protein | - |
| KIM45_RS09820 (KIM45_09680) | - | 2002459..2002920 (+) | 462 | WP_001209480.1 | sigma-E factor regulatory protein RseB domain-containing protein | - |
| KIM45_RS09825 (KIM45_09685) | - | 2002898..2003254 (+) | 357 | WP_000403783.1 | hypothetical protein | - |
| KIM45_RS09830 (KIM45_09690) | - | 2003305..2003517 (+) | 213 | WP_000935422.1 | hypothetical protein | - |
| KIM45_RS09835 (KIM45_09695) | - | 2003551..2003733 (+) | 183 | WP_001224662.1 | DUF7167 family protein | - |
| KIM45_RS09840 (KIM45_09700) | - | 2003726..2003902 (+) | 177 | WP_000753069.1 | hypothetical protein | - |
| KIM45_RS09845 (KIM45_09705) | - | 2003899..2004411 (+) | 513 | Protein_1907 | ead/Ea22-like family protein | - |
| KIM45_RS09850 (KIM45_09710) | - | 2004622..2004840 (+) | 219 | WP_000209152.1 | DUF4014 family protein | - |
| KIM45_RS09855 (KIM45_09715) | - | 2004842..2005207 (+) | 366 | WP_001229296.1 | HNH endonuclease | - |
| KIM45_RS09860 (KIM45_09720) | - | 2005204..2005548 (+) | 345 | WP_000206830.1 | hypothetical protein | - |
| KIM45_RS09865 (KIM45_09725) | - | 2005753..2006052 (-) | 300 | WP_000220601.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KIM45_RS09870 (KIM45_09730) | - | 2006058..2006315 (-) | 258 | WP_001260977.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| KIM45_RS09875 (KIM45_09735) | - | 2006451..2006723 (+) | 273 | WP_001342259.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 24147.02 Da Isoelectric Point: 9.2180
>NTDB_id=566033 KIM45_RS09675 WP_000839153.1 1981120..1981749(+) (sxy/tfoX) [Escherichia coli strain 99_0849]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
Nucleotide
Download Length: 630 bp
>NTDB_id=566033 KIM45_RS09675 WP_000839153.1 1981120..1981749(+) (sxy/tfoX) [Escherichia coli strain 99_0849]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sxy/tfoX | Escherichia coli BW25113 strain K-12 |
100 |
100 |
1 |