Detailed information
Bioinformatically predicted
Overview
| Name | sxy/tfoX | Type | Regulator |
| Locus tag | KIM46_RS10045 | Genome accession | NZ_CP074764 |
| Coordinates | 2018157..2018786 (+) | Length | 209 a.a. |
| NCBI ID | WP_000839153.1 | Uniprot ID | A0A9Q6Y251 |
| Organism | Escherichia coli strain B1_2 | ||
| Function | positive regulator of competence gene (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2005654..2043981 | 2018157..2018786 | within | 0 |
Gene organization within MGE regions
Location: 2005654..2043981
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KIM46_RS09995 (KIM46_09925) | uup | 2006984..2008891 (+) | 1908 | WP_000053122.1 | ABC transporter ATP-binding protein | - |
| KIM46_RS10000 (KIM46_09930) | pqiA | 2009021..2010274 (+) | 1254 | WP_000333166.1 | membrane integrity-associated transporter subunit PqiA | - |
| KIM46_RS10005 (KIM46_09935) | pqiB | 2010279..2011919 (+) | 1641 | WP_000445533.1 | intermembrane transport protein PqiB | - |
| KIM46_RS10010 (KIM46_09940) | pqiC | 2011916..2012479 (+) | 564 | WP_000759123.1 | membrane integrity-associated transporter subunit PqiC | - |
| KIM46_RS10015 (KIM46_09945) | rmf | 2012735..2012902 (+) | 168 | WP_000828648.1 | ribosome modulation factor | - |
| KIM46_RS10020 (KIM46_09950) | fabA | 2012972..2013490 (-) | 519 | WP_000227927.1 | bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase | - |
| KIM46_RS10025 (KIM46_09955) | ycbZ | 2013559..2015319 (-) | 1761 | WP_000156528.1 | AAA family ATPase | - |
| KIM46_RS10030 (KIM46_09960) | matP | 2015505..2015957 (+) | 453 | WP_000877161.1 | macrodomain Ter protein MatP | - |
| KIM46_RS10035 (KIM46_09965) | ompA | 2016032..2017072 (-) | 1041 | WP_000750416.1 | porin OmpA | - |
| KIM46_RS10040 (KIM46_09970) | sulA | 2017429..2017938 (-) | 510 | WP_000288710.1 | SOS-induced cell division inhibitor SulA | - |
| KIM46_RS10045 (KIM46_09975) | sxy/tfoX | 2018157..2018786 (+) | 630 | WP_000839153.1 | CRP-S regulon transcriptional coactivator Sxy | Regulator |
| KIM46_RS10050 (KIM46_09980) | yccS | 2018749..2020911 (-) | 2163 | WP_000875023.1 | YccS family putative transporter | - |
| KIM46_RS10055 (KIM46_09985) | yccF | 2020921..2021367 (-) | 447 | WP_001261235.1 | YccF domain-containing protein | - |
| KIM46_RS10060 (KIM46_09990) | helD | 2021490..2023544 (+) | 2055 | WP_419755841.1 | DNA helicase IV | - |
| KIM46_RS10065 (KIM46_09995) | mgsA | 2023576..2024034 (-) | 459 | WP_000424181.1 | methylglyoxal synthase | - |
| KIM46_RS10070 (KIM46_10000) | csgI | 2024130..2024792 (-) | 663 | WP_000847791.1 | DUF2057 family protein | - |
| KIM46_RS10075 (KIM46_10005) | yccU | 2024965..2025378 (+) | 414 | WP_000665217.1 | CoA-binding protein | - |
| KIM46_RS10080 (KIM46_10010) | hspQ | 2025423..2025740 (-) | 318 | WP_001295356.1 | heat shock protein HspQ | - |
| KIM46_RS10085 (KIM46_10015) | rlmI | 2025798..2026988 (-) | 1191 | WP_000116301.1 | 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI | - |
| KIM46_RS10090 (KIM46_10020) | yccX | 2027083..2027361 (+) | 279 | WP_000048244.1 | acylphosphatase | - |
| KIM46_RS10095 (KIM46_10025) | tusE | 2027358..2027687 (-) | 330 | WP_000904442.1 | sulfurtransferase TusE | - |
| KIM46_RS10100 (KIM46_10030) | yccA | 2027778..2028437 (-) | 660 | WP_000375138.1 | FtsH protease modulator YccA | - |
| KIM46_RS10105 (KIM46_10035) | - | 2028845..2029864 (-) | 1020 | WP_001299351.1 | tyrosine-type recombinase/integrase | - |
| KIM46_RS10110 (KIM46_10040) | - | 2029842..2030084 (-) | 243 | WP_000273151.1 | DUF4224 domain-containing protein | - |
| KIM46_RS10115 (KIM46_10045) | - | 2030152..2032602 (-) | 2451 | WP_419755816.1 | 3'-5' exoribonuclease domain-containing protein | - |
| KIM46_RS10120 (KIM46_10050) | - | 2032697..2032885 (-) | 189 | WP_000199475.1 | DUF1482 family protein | - |
| KIM46_RS10125 (KIM46_10055) | dicB | 2032882..2033070 (-) | 189 | WP_000449175.1 | cell division inhibition protein DicB | - |
| KIM46_RS10130 (KIM46_10060) | - | 2033471..2033635 (+) | 165 | WP_001331716.1 | hypothetical protein | - |
| KIM46_RS10135 (KIM46_10065) | ydfC | 2033639..2033857 (-) | 219 | WP_153781574.1 | protein YdfC | - |
| KIM46_RS10140 | - | 2033950..2034150 (+) | 201 | WP_024182289.1 | ECs_2282 family putative zinc-binding protein | - |
| KIM46_RS10145 (KIM46_10075) | - | 2034564..2034866 (+) | 303 | WP_000692026.1 | type II toxin-antitoxin system HigB family toxin | - |
| KIM46_RS10150 (KIM46_10080) | - | 2034869..2035228 (+) | 360 | WP_001022415.1 | helix-turn-helix domain-containing protein | - |
| KIM46_RS10155 (KIM46_10085) | - | 2035275..2035667 (-) | 393 | WP_000578360.1 | helix-turn-helix domain-containing protein | - |
| KIM46_RS10160 (KIM46_10090) | - | 2035794..2036054 (+) | 261 | WP_001172789.1 | transcriptional regulator | - |
| KIM46_RS10165 (KIM46_10095) | - | 2036051..2036488 (+) | 438 | WP_000693932.1 | toxin YdaT family protein | - |
| KIM46_RS10170 (KIM46_10100) | - | 2036575..2037585 (+) | 1011 | WP_000729535.1 | DUF1376 domain-containing protein | - |
| KIM46_RS10175 (KIM46_10105) | - | 2037578..2038039 (+) | 462 | WP_000139444.1 | replication protein P | - |
| KIM46_RS10180 (KIM46_10110) | - | 2038073..2038798 (+) | 726 | WP_000450641.1 | DUF1627 domain-containing protein | - |
| KIM46_RS10185 (KIM46_10115) | - | 2038814..2039206 (+) | 393 | WP_419755817.1 | DUF977 family protein | - |
| KIM46_RS10190 (KIM46_10120) | - | 2039203..2039499 (+) | 297 | WP_001266133.1 | DUF4406 domain-containing protein | - |
| KIM46_RS10195 (KIM46_10125) | - | 2039496..2039957 (+) | 462 | WP_001209480.1 | sigma-E factor regulatory protein RseB domain-containing protein | - |
| KIM46_RS10200 (KIM46_10130) | - | 2039935..2040291 (+) | 357 | WP_000403783.1 | hypothetical protein | - |
| KIM46_RS10205 (KIM46_10135) | - | 2040342..2040554 (+) | 213 | WP_000935422.1 | hypothetical protein | - |
| KIM46_RS10210 (KIM46_10140) | - | 2040588..2040770 (+) | 183 | WP_001224662.1 | DUF7167 family protein | - |
| KIM46_RS10215 (KIM46_10145) | - | 2040763..2040939 (+) | 177 | WP_000753069.1 | hypothetical protein | - |
| KIM46_RS10220 (KIM46_10150) | - | 2040936..2041448 (+) | 513 | Protein_2003 | ead/Ea22-like family protein | - |
| KIM46_RS10225 (KIM46_10155) | - | 2041659..2041877 (+) | 219 | WP_000209152.1 | DUF4014 family protein | - |
| KIM46_RS10230 (KIM46_10160) | - | 2041879..2042244 (+) | 366 | WP_001229296.1 | HNH endonuclease | - |
| KIM46_RS10235 (KIM46_10165) | - | 2042241..2042585 (+) | 345 | WP_000206830.1 | hypothetical protein | - |
| KIM46_RS10240 (KIM46_10170) | - | 2042790..2043089 (-) | 300 | WP_000220601.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KIM46_RS10245 (KIM46_10175) | - | 2043095..2043352 (-) | 258 | WP_001260977.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| KIM46_RS10250 (KIM46_10180) | - | 2043488..2043760 (+) | 273 | WP_001342259.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 24147.02 Da Isoelectric Point: 9.2180
>NTDB_id=566017 KIM46_RS10045 WP_000839153.1 2018157..2018786(+) (sxy/tfoX) [Escherichia coli strain B1_2]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
Nucleotide
Download Length: 630 bp
>NTDB_id=566017 KIM46_RS10045 WP_000839153.1 2018157..2018786(+) (sxy/tfoX) [Escherichia coli strain B1_2]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sxy/tfoX | Escherichia coli BW25113 strain K-12 |
100 |
100 |
1 |