Detailed information NTG0056581

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SITYG_RS09760
• Genome accession: NZ_AP014880
• Coordinates: 1906610..1909168 (-)
• Length: 852 a.a.
• NCBI ID: WP_096363253.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain TYG1620
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1901610..1914168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS09735 (SITYG_19170)	-	1902241..1902747 (+)	507	WP_096363251.1	helix-turn-helix domain-containing protein	-
SITYG_RS09740 (SITYG_19180)	-	1902731..1903240 (+)	510	WP_162287173.1	RDD family protein	-
SITYG_RS09745 (SITYG_19190)	hexB	1903386..1905332 (-)	1947	WP_021003321.1	DNA mismatch repair endonuclease MutL	Machinery gene
SITYG_RS09750 (SITYG_19200)	brsR	1905574..1906014 (+)	441	WP_041823295.1	LytTR family DNA-binding domain-containing protein	Regulator
SITYG_RS09755 (SITYG_19210)	-	1906011..1906469 (+)	459	WP_020999243.1	DUF3021 domain-containing protein	-
SITYG_RS09760 (SITYG_19220)	hexA	1906610..1909168 (-)	2559	WP_096363253.1	DNA mismatch repair protein MutS	Machinery gene
SITYG_RS09765 (SITYG_19230)	argR	1909331..1909771 (-)	441	WP_003075336.1	arginine repressor	-
SITYG_RS09770 (SITYG_19240)	argS	1909875..1911563 (+)	1689	WP_096363254.1	arginine--tRNA ligase	-
SITYG_RS09775 (SITYG_19250)	nrdI	1911615..1912070 (-)	456	WP_020999246.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
SITYG_RS09780 (SITYG_19260)	-	1912146..1912655 (-)	510	WP_096363255.1	hypothetical protein	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 96200.67 Da
• Isoelectric Point: 4.9722

>NTDB_id=56581 SITYG_RS09760 WP_096363253.1 1906610..1909168(-) (hexA) [Streptococcus intermedius strain TYG1620]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSEKPIPMAGVPYHSVQQYIDVLI
ESGYKVAIAEQVEDPKKAVGVVKREVVQVITPGTTVDSSKPDSQNNFLVALDKLEDFYGLAYMDVVTGEFQVTTLSDFNM
VCGEIRNLRAREVVLGYELPEAEHQVLANQMNLLLSQVETAFEDVQLLGDELSRLEYQVAGKLLEYVHQTQLRELSHLKR
VHHYEIKDFLQMDYATMTSLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRRWIQHPLLDKERILKRQDVVQVFLDHFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILQGIDHPVLGQLIENLDDIPELANLIQSAISP
DAPNVITEGNIIQTGFDETLDKYRVVLRDGTSWIADIEAKEKAASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFIRIREEVGKYIKRLQSLAQTLATVDVLQSFAAVAEKQRFVRPEFI
ERPSIEIDKGRHAVVEKVMGAQTYIPNSISMDENVNLQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAERAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATEHSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TDLSTSLTQLENVHVATLEKDGKVTFLHKIEAGPADKSYGIHVARIAGLPDDLLMRADQILARLEEQANEKPSLNPSNKG
ANDSKENQVSEQISLFTETTESPILDELRQLDIYNMTPMEVMLAVAEMKKHL

Nucleotide

• Length: 2559 bp

>NTDB_id=56581 SITYG_RS09760 WP_096363253.1 1906610..1909168(-) (hexA) [Streptococcus intermedius strain TYG1620]
ATGACAAAAGAAAAACTATCTCCGGGGATGCAACAGTATTTAGATATAAAAAAAGATTATCCGGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAAGCCAATTCCGATGGCAGGAGTTCCCTATCATTCGGTGCAACAATATATTGATGTTTTAATT
GAATCGGGCTATAAAGTAGCGATTGCAGAGCAGGTGGAAGATCCTAAAAAAGCAGTTGGTGTAGTCAAACGTGAGGTGGT
ACAAGTCATCACACCGGGGACAACCGTTGATTCTTCAAAACCAGATAGTCAAAATAATTTCTTGGTAGCTTTAGATAAGC
TAGAAGATTTCTATGGGCTAGCTTATATGGATGTGGTAACTGGTGAATTTCAGGTGACAACTCTCAGTGACTTTAACATG
GTTTGTGGGGAAATTCGAAACCTACGAGCGCGTGAAGTGGTATTGGGATATGAATTACCTGAAGCAGAGCACCAAGTGTT
GGCAAATCAAATGAATTTGTTATTATCACAGGTGGAAACTGCTTTTGAAGATGTTCAGCTATTAGGAGATGAATTGTCTC
GCTTAGAATATCAAGTAGCTGGGAAACTGTTAGAATATGTCCACCAGACGCAGCTGCGTGAGCTTAGTCACTTAAAGCGA
GTTCATCATTATGAAATTAAAGATTTCTTACAGATGGACTATGCAACTATGACAAGTCTAGATTTAACGGAGAATGCACG
GACGGGGAAGAAGCATGGCAGTCTTTATTGGTTGATGGACGAGACCAAGACAGCCATGGGGACGCGGCTTCTAAGAAGAT
GGATCCAGCATCCGTTGCTTGATAAGGAACGGATTCTTAAGCGGCAGGATGTCGTACAAGTCTTTTTAGATCATTTTTTT
GAGCGTAGTGATTTGGCAGATAGTCTCAAAGGGGTTTATGATATTGAGCGCTTGGCAAGCCGTGTTTCTTTTGGGAAGAC
AAACCCGAAGGATTTATTGCAGTTGGCGGCAACATTGAGCCATGTCCCTCAGATTAAGGGAATTTTACAAGGAATCGATC
ATCCTGTTTTGGGACAGTTGATTGAAAACTTGGATGATATTCCAGAATTGGCAAACTTGATTCAGTCGGCAATTTCTCCT
GATGCTCCAAATGTTATTACGGAAGGGAATATCATTCAAACTGGTTTTGATGAAACCTTAGATAAGTATCGAGTGGTTCT
GCGAGATGGTACGAGCTGGATTGCTGATATTGAAGCGAAAGAAAAAGCAGCTAGTGGGATTAATAATCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTTACTAATTCACAGTTGGAGCACGTACCTAGCCACTTTTTCCGAAAAGCA
ACGTTGAAAAATTCAGAACGATTTGGTACAGAGGAATTGGCTCGTATTGAAGGCGAAATGTTGGAAGCGCGTGAAAAATC
GGCCAATTTAGAGTATGAGATTTTTATACGTATTCGGGAAGAAGTTGGTAAATATATCAAACGATTACAATCCTTGGCAC
AAACTCTAGCAACAGTGGATGTATTGCAGAGTTTTGCAGCAGTTGCTGAAAAGCAACGCTTTGTACGCCCAGAATTTATT
GAACGTCCTTCCATTGAAATCGATAAGGGACGGCATGCGGTTGTAGAAAAGGTTATGGGTGCACAAACTTATATTCCGAA
TAGTATTTCAATGGATGAGAATGTCAATCTTCAGTTAATTACAGGTCCAAATATGAGTGGGAAGTCAACCTATATGCGTC
AATTAGCGATTATTGTTATCATGGCGCAAATGGGTTCCTATGTTTCAGCTGAACGTGCTCAATTACCAATTTTTGATGCC
ATCTTCACTCGAATTGGTGCAGCAGATGACTTGGTATCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCAAATCA
TGCTATTTCTCAAGCGACTGAACACTCTCTTATTCTTTTTGATGAGTTGGGAAGAGGAACAGCAACATATGATGGGATGG
CTCTTGCTCAGGCAATTATTGAATATATCCACAATCGAACAGGAGCAAAGACCCTTTTTGCTACACACTATCATGAGTTG
ACAGACTTGTCAACTAGCTTGACACAGTTAGAAAATGTTCATGTGGCAACTTTAGAAAAAGATGGGAAAGTGACTTTTCT
TCATAAGATTGAAGCTGGTCCTGCAGATAAATCTTATGGGATTCATGTTGCAAGAATTGCAGGTTTACCAGATGATTTGT
TGATGAGAGCCGACCAGATACTAGCAAGACTAGAAGAACAAGCAAATGAGAAACCATCTCTCAATCCTTCTAATAAAGGA
GCTAATGATAGTAAAGAAAATCAAGTATCTGAGCAGATATCTTTATTCACAGAAACAACTGAATCACCTATTTTAGATGA
ACTACGTCAGTTGGATATTTATAATATGACCCCAATGGAAGTGATGTTAGCTGTAGCTGAGATGAAAAAACATCTCTGA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (255-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	75.352	100	0.754
mutS	Pseudomonas stutzeri strain ATCC 17587	36.659	100	0.371