Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KH263_RS05655 Genome accession   NZ_CP074685
Coordinates   1133327..1133983 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain VTX9     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128327..1138983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KH263_RS05625 (KH263_05625) oppF 1128856..1129773 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  KH263_RS05630 (KH263_05630) - 1129880..1131067 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  KH263_RS05635 (KH263_05635) - 1131185..1131763 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  KH263_RS05640 (KH263_05640) spx 1131942..1132337 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  KH263_RS05645 (KH263_05645) - 1132395..1133051 (-) 657 WP_003155033.1 TerC family protein -
  KH263_RS05650 (KH263_05650) - 1133234..1133344 (+) 111 Protein_1063 adaptor protein MecA -
  KH263_RS05655 (KH263_05655) mecA 1133327..1133983 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  KH263_RS05660 (KH263_05660) - 1134134..1135294 (+) 1161 WP_165625605.1 competence protein CoiA family protein -
  KH263_RS05665 (KH263_05665) pepF 1135522..1137351 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  KH263_RS05670 (KH263_05670) - 1137389..1137556 (-) 168 WP_003155026.1 hypothetical protein -
  KH263_RS05675 (KH263_05675) spxH 1137842..1138744 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=565715 KH263_RS05655 WP_003155032.1 1133327..1133983(+) (mecA) [Bacillus velezensis strain VTX9]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=565715 KH263_RS05655 WP_003155032.1 1133327..1133983(+) (mecA) [Bacillus velezensis strain VTX9]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895