Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SITYG_RS09010 Genome accession   NZ_AP014880
Coordinates   1777863..1779992 (-) Length   709 a.a.
NCBI ID   WP_096363352.1    Uniprot ID   -
Organism   Streptococcus intermedius strain TYG1620     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1772863..1784992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS08980 (SITYG_17780) - 1772946..1773653 (-) 708 WP_003074030.1 L-ribulose-5-phosphate 4-epimerase -
  SITYG_RS08985 (SITYG_17790) - 1773656..1774519 (-) 864 WP_096363201.1 L-ribulose-5-phosphate 3-epimerase -
  SITYG_RS08990 (SITYG_17800) - 1774525..1775190 (-) 666 WP_021003250.1 3-keto-L-gulonate-6-phosphate decarboxylase UlaD -
  SITYG_RS08995 (SITYG_17810) - 1775236..1775721 (-) 486 WP_003074024.1 PTS sugar transporter subunit IIA -
  SITYG_RS09000 (SITYG_17820) - 1775923..1776204 (-) 282 WP_003074022.1 PTS sugar transporter subunit IIB -
  SITYG_RS09005 (SITYG_17830) - 1776235..1777695 (-) 1461 WP_009569486.1 PTS ascorbate transporter subunit IIC -
  SITYG_RS09010 (SITYG_17840) clpE 1777863..1779992 (-) 2130 WP_096363352.1 AAA family ATPase Regulator
  SITYG_RS09015 (SITYG_17850) - 1780370..1780675 (-) 306 WP_009569488.1 hypothetical protein -
  SITYG_RS09020 (SITYG_17860) - 1780675..1781085 (-) 411 WP_009569489.1 hypothetical protein -
  SITYG_RS09025 (SITYG_17870) - 1781067..1782326 (-) 1260 WP_096363202.1 lipase family alpha/beta hydrolase -
  SITYG_RS09030 (SITYG_17880) - 1782323..1782715 (-) 393 WP_009569492.1 DUF1310 family protein -
  SITYG_RS09035 (SITYG_17890) - 1782770..1782952 (-) 183 WP_009569494.1 hypothetical protein -
  SITYG_RS09040 (SITYG_17900) - 1782955..1783341 (-) 387 WP_096363203.1 DUF1310 family protein -
  SITYG_RS09045 (SITYG_17910) - 1783384..1783566 (-) 183 WP_009569497.1 hypothetical protein -
  SITYG_RS09050 (SITYG_17920) - 1783571..1783958 (-) 388 Protein_1756 DUF1310 family protein -
  SITYG_RS09055 (SITYG_17940) - 1784002..1784184 (-) 183 WP_009569502.1 hypothetical protein -
  SITYG_RS09060 (SITYG_17950) - 1784181..1784573 (-) 393 WP_009569503.1 DUF1310 family protein -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 78897.04 Da        Isoelectric Point: 4.8162

>NTDB_id=56563 SITYG_RS09010 WP_096363352.1 1777863..1779992(-) (clpE) [Streptococcus intermedius strain TYG1620]
MNNNYNNFDNMDDLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQVAEGQASQMQGQAGELKQDGILMK
LGRNLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDIS
GLEAGTQYRGSFEENIQNLVSEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILSDDVLKAAVDFSIQYIPQRSLPDKAIDLVDVTAAHL
AAQHPVTDVHTVEREIAEQKKKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQM
GTSDIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDIFGTKEAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFK
NTVIIATSNAGFGYESFTGDEEKDRKIIDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVDLMLDEVNQTLAKKDIMLT
VTDAAKHYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDAKHLLADLKDDELVIEEAKEHQTKK

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=56563 SITYG_RS09010 WP_096363352.1 1777863..1779992(-) (clpE) [Streptococcus intermedius strain TYG1620]
ATGAATAATAATTATAACAACTTTGATAATATGGATGATCTTTTCAATCAATTGATGGGAAGGATGGGCGGTTTTAACAG
TGAAAATCGGCGTTATCTTATCAATGGACGTGAAGTGACACCAGAAGAATTTGCACAATATCGTGCAACAGGTAAATTAC
CGAAGCAAGTAGCGGAAGGTCAGGCATCACAAATGCAAGGACAAGCAGGTGAGCTTAAACAAGATGGTATTTTAATGAAG
TTAGGGCGTAATTTGACAGAAGAAGCACGTCAAGATATGTTAGATCCTGTTATTGGACGCAATAAGGAAATTCAAGAAAC
GGCTGAAATTCTTTCTCGGCGAACGAAAAACAATCCAGTATTAGTCGGAGACGCTGGAGTTGGTAAGACTGCAGTTGTCG
AAGGTTTAGCGCAAGCGATTGTTAATGGAGATGTTCCTGCAGCCATTAAGAATAAAGAGATTGTTTCTATTGATATTTCT
GGTTTAGAAGCAGGGACACAGTATCGTGGTAGTTTTGAAGAAAATATTCAAAATTTAGTATCTGAAGTGAAAGAGGCTGG
CAATATCATTCTCTTCTTTGATGAAATTCATCAAATTCTGGGCGCTGGAAGCACAGGCGGTGATAGTGGATCAAAAGGTC
TAGCAGATATTTTGAAACCGGCTTTATCTCGTGGTGAACTGACAGTTATCGGTGCGACGACTCAGGATGAATACCGAAAT
ACCATTTTGAAGAATGCAGCTCTAGCTCGTCGCTTCAATGAAGTAAAAGTCAATGCCCCATCTGCAGAAGATACTTACAA
GATTTTGCAAGGAATTCGTGATTTATACGAAAAACACCACAATGTCATCTTGTCAGATGACGTGTTAAAAGCTGCCGTGG
ATTTCTCTATTCAATACATTCCGCAACGCAGCTTGCCGGATAAAGCGATTGACCTGGTGGATGTGACAGCGGCTCATTTA
GCAGCTCAACATCCTGTTACAGATGTGCATACAGTAGAACGTGAAATTGCGGAGCAAAAGAAAAAGCAAGAAGCTGCGGT
TGAAAAAGAAGACTTTGAAACTGCTTTGAATGCCAAGATGCGTATTGAAGAGCTAGAAAAAAAGATTGAAAATCATACGG
AAGACATGAAAGTAACTGCAACTGTCAATGATGTAGCAGAATCTGTAGAACGTATGACGGGTATTCCTGTTTCCCAAATG
GGGACTAGTGATATTGAACGGTTGAAAGAGATGAATGCGCGATTGAAGACAAAAGTCATTGGACAAAACGAGGCAGTTGA
AGCAGTGGCGCGCGCTATTCGTCGGAATCGTGCAGGTTTTGATGAAGGAAATCGTCCGATTGGTAGCTTTCTCTTTGTTG
GCCCAACTGGTGTTGGAAAAACAGAGCTAGCGAAGCAATTGGCACTTGATATATTTGGTACTAAAGAAGCTATTATCCGT
TTGGACATGTCTGAATACTCTGACCGCACAGCTGTGTCGAAATTGATTGGTACAACAGCTGGTTATGTGGGGTATGATGA
CAATAGCAACACGTTGACAGAACGTGTTCGTCGGAATCCTTACTCTATCATCTTGCTGGACGAAATTGAAAAAGCCGATC
CACAAGTCATCACATTGTTACTACAAGTTTTGGACGATGGACGTCTGACAGATGGACAAGGAAATACTGTCAACTTTAAG
AACACAGTTATTATTGCTACATCAAATGCTGGATTTGGGTATGAAAGCTTTACTGGTGATGAGGAAAAGGATAGGAAGAT
TATCGATCGCTTAAAACCATACTTCCGTCCAGAATTCTTGAATCGCTTCAATGCAGTCATTGAATTCTCTCATCTTGGTA
AAGAGGATTTAGCTGAAATCGTCGACTTGATGTTGGATGAGGTCAACCAAACACTTGCTAAGAAAGACATTATGCTAACA
GTAACAGATGCGGCAAAACATTATCTAGCAGAAGAGGGATATGATGAAGTTATGGGTGTTCGTCCGCTTCGTCGTGTGAT
TGAGCAACAAATCCGTGATAAGGTAACAGACTATCATCTTGATCATTTAGATGCGAAACATCTTCTTGCAGATTTGAAAG
ATGATGAATTAGTTATCGAAGAAGCGAAAGAGCATCAAACTAAAAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(261-356)

AAA domain (Cdc48 subfamily) (AAA_2)

(445-605)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(612-682)

ATPase family associated with various cellular activities (AAA) (AAA)

(120-252)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.889

97.461

0.457
  clpC Lactococcus lactis subsp. cremoris KW2

51.347

88.999

0.457
  clpE Streptococcus pneumoniae R6

45.546

98.166

0.447
  clpE Streptococcus pneumoniae D39

45.546

98.166

0.447
  clpE Streptococcus pneumoniae Rx1

45.546

98.166

0.447
  clpE Streptococcus pneumoniae TIGR4

45.31

97.743

0.443
  clpC Bacillus subtilis subsp. subtilis str. 168

47.214

91.114

0.43
  clpC Streptococcus pneumoniae Rx1

42.613

90.691

0.386
  clpC Streptococcus pneumoniae D39

42.613

90.691

0.386
  clpC Streptococcus pneumoniae TIGR4

42.457

90.691

0.385
  clpC Streptococcus mutans UA159

43.922

87.024

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.506

86.883

0.378
  clpC Streptococcus thermophilus LMD-9

42.626

87.024

0.371
  clpC Streptococcus thermophilus LMG 18311

42.464

87.024

0.37

Multiple sequence alignment