Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   MKD48_RS05435 Genome accession   NZ_CP092475
Coordinates   1028678..1029952 (-) Length   424 a.a.
NCBI ID   WP_001279338.1    Uniprot ID   A0A0H2XGV4
Organism   Staphylococcus aureus strain P5     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1023678..1034952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKD48_RS05420 - 1025964..1026056 (+) 93 WP_001789987.1 hypothetical protein -
  MKD48_RS05425 - 1026036..1026941 (-) 906 WP_000184370.1 transglycosylase domain-containing protein -
  MKD48_RS05430 tyrS 1027322..1028584 (+) 1263 WP_000186037.1 tyrosine--tRNA ligase -
  MKD48_RS05435 htrA 1028678..1029952 (-) 1275 WP_001279338.1 trypsin-like peptidase domain-containing protein Regulator
  MKD48_RS05440 - 1030124..1030741 (+) 618 WP_000287588.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  MKD48_RS05445 nagE 1030869..1032335 (+) 1467 WP_000276367.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  MKD48_RS05450 - 1032442..1033572 (+) 1131 WP_000721707.1 HAD family hydrolase -
  MKD48_RS05455 - 1033533..1033628 (-) 96 WP_031789489.1 hypothetical protein -

Sequence

Protein


Download         Length: 424 a.a.        Molecular weight: 45802.98 Da        Isoelectric Point: 9.9696

>NTDB_id=565362 MKD48_RS05435 WP_001279338.1 1028678..1029952(-) (htrA) [Staphylococcus aureus strain P5]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide


Download         Length: 1275 bp        

>NTDB_id=565362 MKD48_RS05435 WP_001279338.1 1028678..1029952(-) (htrA) [Staphylococcus aureus strain P5]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTCCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-269)

PDZ domain (PDZ_2)

(307-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

39.055

94.811

0.37