Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   - Genome accession   NC_007432
Coordinates   64823..64870 (+) Length   16 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus agalactiae A909     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 59823..69870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAK_RS00385 (SAK_0078) purK 59825..60916 (+) 1092 WP_001084008.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SAK_RS00390 (SAK_0079) - 60969..62360 (+) 1392 WP_001079797.1 hypothetical protein -
  SAK_RS00395 (SAK_0080) purB 62382..63680 (+) 1299 WP_000572890.1 adenylosuccinate lyase -
  SAK_RS00400 (SAK_0081) - 63833..64741 (+) 909 WP_000912095.1 helix-turn-helix domain-containing protein -
  - comS 64823..64870 (+) 48 - - Regulator
  SAK_RS00405 (SAK_0082) ruvB 64942..65940 (+) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB -
  SAK_RS00410 (SAK_0083) - 66092..66529 (+) 438 WP_000754818.1 low molecular weight protein-tyrosine-phosphatase -
  SAK_RS00415 (SAK_0084) - 66536..66916 (+) 381 WP_000787702.1 membrane protein -
  SAK_RS00420 (SAK_0085) - 66913..68691 (+) 1779 WP_001220907.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 16 a.a.        Molecular weight: 1983.42 Da        Isoelectric Point: 9.1500

>NTDB_id=565 64823..64870(+) (comS) [Streptococcus agalactiae A909]
MFKVFFTVMTGVFWWG

Nucleotide


Download         Length: 48 bp        

>NTDB_id=565 64823..64870(+) (comS) [Streptococcus agalactiae A909]
ATGTTTAAAGTATTTTTTACAGTAATGACTGGGGTTTTCTGGTGGGGA

XIP

This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

TGVFWWG


Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

53.846

81.25

0.437

Multiple sequence alignment