Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   MAK06_RS10015 Genome accession   NZ_CP091876
Coordinates   2015991..2016704 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain FRI-1169     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2010991..2021704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MAK06_RS09955 (MAK06_03920) - 2012193..2012456 (-) 264 WP_001205732.1 hypothetical protein -
  MAK06_RS09960 (MAK06_03915) - 2012465..2012725 (-) 261 WP_000291510.1 DUF1108 family protein -
  MAK06_RS09965 (MAK06_03910) - 2012730..2013032 (-) 303 WP_000165371.1 DUF2482 family protein -
  MAK06_RS09970 (MAK06_03905) - 2013127..2013288 (-) 162 WP_000048132.1 DUF1270 family protein -
  MAK06_RS09975 (MAK06_03900) - 2013285..2013608 (-) 324 WP_001120201.1 DUF771 domain-containing protein -
  MAK06_RS09980 (MAK06_03895) - 2013663..2014043 (+) 381 WP_000762521.1 DUF2513 domain-containing protein -
  MAK06_RS09985 (MAK06_03890) - 2014030..2014227 (-) 198 WP_001148862.1 hypothetical protein -
  MAK06_RS09990 (MAK06_03885) - 2014243..2014995 (-) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  MAK06_RS09995 (MAK06_03880) - 2015046..2015375 (+) 330 WP_000128907.1 hypothetical protein -
  MAK06_RS10000 (MAK06_03875) - 2015364..2015579 (-) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  MAK06_RS10005 (MAK06_03870) - 2015595..2015858 (-) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  MAK06_RS10010 (MAK06_03865) - 2015855..2016028 (-) 174 WP_001801500.1 hypothetical protein -
  MAK06_RS10015 (MAK06_03860) irvR 2015991..2016704 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  MAK06_RS10020 (MAK06_03855) - 2016720..2017652 (+) 933 WP_000759682.1 exonuclease domain-containing protein -
  MAK06_RS10025 (MAK06_03850) - 2017658..2017999 (+) 342 WP_000591749.1 hypothetical protein -
  MAK06_RS10030 (MAK06_03845) - 2018203..2018370 (+) 168 WP_000705247.1 hypothetical protein -
  MAK06_RS10035 (MAK06_03840) - 2018510..2019049 (+) 540 WP_238097446.1 type II toxin-antitoxin system PemK/MazF family toxin -
  MAK06_RS10040 (MAK06_03835) - 2019222..2020259 (+) 1038 WP_000857198.1 site-specific integrase -
  MAK06_RS10045 (MAK06_03830) sph 2020310..2021140 (+) 831 Protein_1940 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=563934 MAK06_RS10015 WP_001031454.1 2015991..2016704(+) (irvR) [Staphylococcus aureus strain FRI-1169]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=563934 MAK06_RS10015 WP_001031454.1 2015991..2016704(+) (irvR) [Staphylococcus aureus strain FRI-1169]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401