Detailed information NTG0563598

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: L2I08_RS28005
• Genome accession: NZ_CP091820
• Coordinates: 6423244..6424365 (+)
• Length: 373 a.a.
• NCBI ID: WP_003948877.1
• Uniprot ID: A0ABR4S230
• Organism: Streptomyces sp. NBU3104
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 6418244..6429365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L2I08_RS27985 (L2I08_27985)	-	6418670..6418891 (-)	222	WP_018469953.1	hypothetical protein	-
L2I08_RS27990 (L2I08_27990)	-	6419005..6420747 (-)	1743	WP_217383886.1	sigma factor-like helix-turn-helix DNA-binding protein	-
L2I08_RS27995 (L2I08_27995)	-	6421026..6421601 (+)	576	WP_003948874.1	dihydrofolate reductase family protein	-
L2I08_RS28000 (L2I08_28000)	radA/sms	6421655..6423073 (+)	1419	WP_003948876.1	DNA repair protein RadA	Machinery gene
L2I08_RS28005 (L2I08_28005)	disA	6423244..6424365 (+)	1122	WP_003948877.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
L2I08_RS28010 (L2I08_28010)	-	6424447..6425271 (-)	825	WP_237897035.1	hypothetical protein	-
L2I08_RS28015 (L2I08_28015)	-	6425627..6426376 (+)	750	WP_008404973.1	phosphatase PAP2 family protein	-
L2I08_RS28020 (L2I08_28020)	-	6426489..6427541 (+)	1053	WP_237897036.1	A/G-specific adenine glycosylase	-
L2I08_RS28025 (L2I08_28025)	-	6427759..6428298 (+)	540	WP_003948881.1	SigE family RNA polymerase sigma factor	-
L2I08_RS28030 (L2I08_28030)	-	6428319..6428987 (+)	669	WP_018895477.1	hypothetical protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40243.11 Da
• Isoelectric Point: 5.1034

>NTDB_id=563598 L2I08_RS28005 WP_003948877.1 6423244..6424365(+) (disA) [Streptomyces sp. NBU3104]
MAANDRATAPGKSGGPGADGLMRASLSAVAPGTQLRDGLERILRGNTGGLIVLGWDRTVESMCTGGFVLDVEFSATRLRE
LCKLDGGIVLDKDLTKILRAGVQLVPDPTIPTDETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIAAEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVDEALAELGKLSHTELLELPVVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAI
IDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=563598 L2I08_RS28005 WP_003948877.1 6423244..6424365(+) (disA) [Streptomyces sp. NBU3104]
GTGGCAGCCAATGACCGGGCAACGGCCCCCGGCAAGTCCGGCGGGCCCGGTGCCGACGGGCTGATGCGTGCCTCGCTGAG
CGCCGTCGCCCCCGGCACCCAGCTGCGGGACGGGCTGGAGCGGATTCTGCGGGGGAACACCGGCGGACTCATCGTGCTCG
GCTGGGACAGGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTCGAGTTCTCGGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACCTCACCAAGATCCTGCGCGCCGGAGTCCAGCTCGTCCCCGA
CCCGACCATCCCCACCGACGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGGTCAACTTCCCCGTGG
TCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCCGCCATC
CTCTCCCGCGCCAACCAGGCCCTCGCGACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCCGGCACGCTCTCGGC
GCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCACGGCCGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCGCCG
CCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGCCTGCTCGCCCTCCAGCTGGACGAGCTGATCGCCGGC
GTCGAGCCCGAACGCGAGCTGGTCGTCCGGGACTACGTGCCGGAACCCACGGCGAAGCGTTCCCGGACGGTGGACGAGGC
GCTGGCGGAGCTGGGCAAGCTCAGCCACACCGAGCTGCTCGAACTGCCCGTGGTGGCGCGGGCGCTCGGCTACACCGGCT
CGCCGGAGGCGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGCGGCTGCCCGGGGCCATC
ATCGACCGGCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTGCTGGCGGCCAGTGTGGACGACCTCCAGACGGTGGACGG
CGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• Helix-hairpin-helix motif (HHH_2) (323-358)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.761	0.432