Detailed information NTG0562089

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV32_RS08635
• Genome accession: NZ_CP073898
• Coordinates: 1832910..1833956 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain V1939586
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1827910..1838956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV32_RS08605 (KFV32_08615)	-	1828294..1829535 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV32_RS08610 (KFV32_08620)	-	1829537..1829752 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV32_RS08615 (KFV32_08625)	-	1829893..1830357 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV32_RS08620 (KFV32_08630)	-	1830365..1830649 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV32_RS08625 (KFV32_08635)	-	1831056..1832234 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV32_RS08630 (KFV32_08640)	vraR	1832291..1832920 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV32_RS08635 (KFV32_08645)	vraS	1832910..1833956 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV32_RS08640 (KFV32_08650)	liaF	1833953..1834654 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV32_RS08645 (KFV32_08655)	-	1834669..1835055 (-)	387	WP_001830382.1	hypothetical protein	-
KFV32_RS08650 (KFV32_08660)	map	1835213..1835968 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV32_RS08655 (KFV32_08665)	-	1836142..1837128 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV32_RS08660 (KFV32_08670)	-	1837279..1837815 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=562089 KFV32_RS08635 WP_001830374.1 1832910..1833956(-) (vraS) [Staphylococcus epidermidis strain V1939586]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=562089 KFV32_RS08635 WP_001830374.1 1832910..1833956(-) (vraS) [Staphylococcus epidermidis strain V1939586]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92