Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV32_RS00615 | Genome accession | NZ_CP073898 |
| Coordinates | 130974..132335 (-) | Length | 453 a.a. |
| NCBI ID | WP_001631036.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain V1939586 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 129349..178010 | 130974..132335 | within | 0 |
Gene organization within MGE regions
Location: 129349..178010
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV32_RS00610 (KFV32_00610) | ccrB | 129349..130977 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV32_RS00615 (KFV32_00615) | ccrA | 130974..132335 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV32_RS00620 (KFV32_00620) | - | 132522..133151 (-) | 630 | Protein_124 | hypothetical protein | - |
| KFV32_RS00625 (KFV32_00625) | - | 133160..133498 (+) | 339 | Protein_125 | recombinase family protein | - |
| KFV32_RS00630 (KFV32_00630) | - | 133610..133969 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV32_RS00635 (KFV32_00635) | - | 134176..134502 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV32_RS00640 (KFV32_00640) | - | 134832..136757 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV32_RS00645 (KFV32_00645) | - | 138009..138314 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV32_RS00650 (KFV32_00650) | - | 138512..139375 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV32_RS00655 (KFV32_00655) | - | 139483..140958 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV32_RS00660 (KFV32_00660) | - | 141185..142285 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV32_RS00665 (KFV32_00665) | - | 142278..142649 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV32_RS00670 (KFV32_00670) | - | 142646..144289 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV32_RS00675 (KFV32_00675) | - | 144516..146192 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV32_RS00680 (KFV32_00680) | - | 146298..146636 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV32_RS00685 (KFV32_00685) | - | 146732..147043 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV32_RS00690 (KFV32_00690) | - | 147059..147565 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV32_RS00695 (KFV32_00695) | - | 147593..148039 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV32_RS00700 (KFV32_00700) | - | 148209..149081 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV32_RS00705 (KFV32_00705) | - | 149133..149423 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV32_RS00715 (KFV32_00715) | - | 149646..149801 (+) | 156 | Protein_142 | metal-sensing transcriptional repressor | - |
| KFV32_RS00720 (KFV32_00720) | - | 149798..150556 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV32_RS00725 (KFV32_00725) | - | 150726..150935 (+) | 210 | Protein_144 | heavy metal translocating P-type ATPase | - |
| KFV32_RS00730 (KFV32_00730) | - | 150953..151498 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV32_RS00735 (KFV32_00735) | - | 151941..153197 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV32_RS00740 (KFV32_00740) | - | 153642..154316 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV32_RS00745 (KFV32_00745) | - | 154400..154741 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV32_RS00750 (KFV32_00750) | - | 155538..156281 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV32_RS00755 (KFV32_00755) | - | 156378..156806 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV32_RS00760 (KFV32_00760) | mecA | 156852..158861 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV32_RS00765 (KFV32_00765) | mecR1 | 158958..160715 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV32_RS00770 (KFV32_00770) | mecI | 160715..161086 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV32_RS00775 (KFV32_00775) | psm-mec | 161171..161239 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV32_RS00780 (KFV32_00780) | - | 161573..162703 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| KFV32_RS00785 (KFV32_00785) | cstB | 162817..164151 (-) | 1335 | Protein_156 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV32_RS00790 (KFV32_00790) | - | 164184..165248 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV32_RS00795 (KFV32_00795) | cstR | 165384..165644 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV32_RS00800 (KFV32_00800) | - | 165644..166282 (+) | 639 | Protein_159 | sulfite exporter TauE/SafE family protein | - |
| KFV32_RS00810 (KFV32_00810) | - | 166556..167172 (-) | 617 | Protein_160 | CadD family cadmium resistance transporter | - |
| KFV32_RS00815 (KFV32_00815) | - | 167253..169667 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV32_RS00820 (KFV32_00820) | - | 169660..170025 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV32_RS00825 (KFV32_00825) | - | 170263..170640 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV32_RS00830 (KFV32_00830) | - | 170647..172539 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV32_RS00835 (KFV32_00835) | - | 172734..173057 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV32_RS00840 (KFV32_00840) | - | 173050..173256 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV32_RS00845 (KFV32_00845) | - | 173258..173779 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV32_RS00850 (KFV32_00850) | - | 173798..174109 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV32_RS00855 (KFV32_00855) | - | 174194..174544 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV32_RS00860 (KFV32_00860) | ccrB | 175015..176643 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV32_RS00865 (KFV32_00865) | ccrA | 176664..178010 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53316.45 Da Isoelectric Point: 9.8596
>NTDB_id=562064 KFV32_RS00615 WP_001631036.1 130974..132335(-) (ccrA) [Staphylococcus epidermidis strain V1939586]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=562064 KFV32_RS00615 WP_001631036.1 130974..132335(-) (ccrA) [Staphylococcus epidermidis strain V1939586]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.628 |
97.792 |
0.534 |
| ccrA | Staphylococcus aureus N315 |
50.564 |
97.792 |
0.494 |