Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV31_RS12765 | Genome accession | NZ_CP073890 |
| Coordinates | 2602482..2603828 (+) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus epidermidis strain V1933793 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 2602482..2651143 | 2602482..2603828 | within | 0 |
Gene organization within MGE regions
Location: 2602482..2651143
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV31_RS12765 (KFV31_12775) | ccrA | 2602482..2603828 (+) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
| KFV31_RS12770 (KFV31_12780) | ccrB | 2603849..2605477 (+) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV31_RS12775 (KFV31_12785) | - | 2605948..2606298 (+) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV31_RS12780 (KFV31_12790) | - | 2606383..2606694 (+) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV31_RS12785 (KFV31_12795) | - | 2606713..2607234 (+) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV31_RS12790 (KFV31_12800) | - | 2607236..2607442 (+) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV31_RS12795 (KFV31_12805) | - | 2607435..2607758 (+) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV31_RS12800 (KFV31_12810) | - | 2607953..2609845 (+) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV31_RS12805 (KFV31_12815) | - | 2609852..2610229 (+) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV31_RS12810 (KFV31_12820) | - | 2610467..2610832 (+) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV31_RS12815 (KFV31_12825) | - | 2610825..2613239 (+) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV31_RS12820 (KFV31_12830) | - | 2613320..2613936 (+) | 617 | Protein_2493 | CadD family cadmium resistance transporter | - |
| KFV31_RS12830 (KFV31_12840) | - | 2614210..2614848 (-) | 639 | Protein_2494 | sulfite exporter TauE/SafE family protein | - |
| KFV31_RS12835 (KFV31_12845) | cstR | 2614848..2615108 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV31_RS12840 (KFV31_12850) | - | 2615244..2616308 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV31_RS12845 (KFV31_12855) | cstB | 2616341..2617675 (+) | 1335 | Protein_2497 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV31_RS12850 (KFV31_12860) | - | 2617789..2618919 (-) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| KFV31_RS12855 (KFV31_12865) | psm-mec | 2619253..2619321 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV31_RS12860 (KFV31_12870) | mecI | 2619406..2619777 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV31_RS12865 (KFV31_12875) | mecR1 | 2619777..2621534 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV31_RS12870 (KFV31_12880) | mecA | 2621631..2623640 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV31_RS12875 (KFV31_12885) | - | 2623686..2624114 (-) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV31_RS12880 (KFV31_12890) | - | 2624211..2624954 (-) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV31_RS12885 (KFV31_12895) | - | 2625751..2626140 (-) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV31_RS12890 (KFV31_12900) | - | 2626176..2626850 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV31_RS12895 (KFV31_12905) | - | 2627295..2628551 (-) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV31_RS12900 (KFV31_12910) | - | 2628994..2629539 (-) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV31_RS12905 (KFV31_12915) | - | 2629557..2629766 (-) | 210 | Protein_2509 | heavy metal translocating P-type ATPase | - |
| KFV31_RS12910 (KFV31_12920) | - | 2629936..2630694 (-) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV31_RS12915 (KFV31_12925) | - | 2630691..2630846 (-) | 156 | Protein_2511 | metal-sensing transcriptional repressor | - |
| KFV31_RS12925 (KFV31_12935) | - | 2631069..2631359 (-) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV31_RS12930 (KFV31_12940) | - | 2631411..2632283 (-) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV31_RS12935 (KFV31_12945) | - | 2632453..2632899 (-) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV31_RS12940 (KFV31_12950) | - | 2632927..2633433 (-) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV31_RS12945 (KFV31_12955) | - | 2633449..2633760 (-) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV31_RS12950 (KFV31_12960) | - | 2633856..2634194 (-) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV31_RS12955 (KFV31_12965) | - | 2634300..2635976 (-) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV31_RS12960 (KFV31_12970) | - | 2636203..2637846 (-) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV31_RS12965 (KFV31_12975) | - | 2637843..2638214 (-) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV31_RS12970 (KFV31_12980) | - | 2638207..2639307 (-) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV31_RS12975 (KFV31_12985) | - | 2639534..2641009 (-) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV31_RS12980 (KFV31_12990) | - | 2641117..2641980 (-) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV31_RS12985 (KFV31_12995) | - | 2642178..2642483 (-) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV31_RS12990 (KFV31_13000) | - | 2643735..2645660 (-) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV31_RS12995 (KFV31_13005) | - | 2645990..2646316 (-) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV31_RS13000 (KFV31_13010) | - | 2646523..2646882 (+) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV31_RS13005 (KFV31_13015) | - | 2646994..2647332 (-) | 339 | Protein_2528 | recombinase family protein | - |
| KFV31_RS13010 (KFV31_13020) | - | 2647341..2647970 (+) | 630 | Protein_2529 | hypothetical protein | - |
| KFV31_RS13015 (KFV31_13025) | ccrA | 2648157..2649518 (+) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV31_RS13020 (KFV31_13030) | ccrB | 2649515..2651143 (+) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=561978 KFV31_RS12765 WP_000816499.1 2602482..2603828(+) (ccrA) [Staphylococcus epidermidis strain V1933793]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=561978 KFV31_RS12765 WP_000816499.1 2602482..2603828(+) (ccrA) [Staphylococcus epidermidis strain V1933793]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |